因与血管免疫母细胞性淋巴结病相关的显著骨髓纤维化导致的严重全血细胞减少。

Severe pancytopenia due to marked marrow fibrosis associated with angioimmunoblastic lymphadenopathy.

作者信息

Brenner B, Green J, Rosenbaum H, Ben Arieh Y, Nagler A, Tatarsky I

出版信息

Acta Haematol. 1985;74(1):43-4. doi: 10.1159/000206163.

DOI:10.1159/000206163

Abstract

A patient with angioimmunoblastic lymphadenopathy (AILD) is presented. Manifestations of the disease appeared after short-term treatment with oxprenolol hydrochloride. Following treatment with prednisone, the patient remained in remission for 25 months. The disease relapsed following reuse of oxprenolol hydrochloride. Severe pancytopenia due to bone marrow involvement by AILD and myelofibrosis led to a fatal outcome. The association of AILD and myelofibrosis has been rarely encountered and is hereby discussed. In addition, the possible relationship between AILD and oxprenolol hydrochloride is considered.

摘要

本文报告了一例血管免疫母细胞性淋巴结病（AILD）患者。该疾病的症状出现在短期服用盐酸氧烯洛尔治疗之后。使用泼尼松治疗后，患者缓解了25个月。再次使用盐酸氧烯洛尔后疾病复发。AILD累及骨髓和骨髓纤维化导致的严重全血细胞减少症导致了致命的结局。AILD与骨髓纤维化的关联很少见，在此进行讨论。此外，还考虑了AILD与盐酸氧烯洛尔之间可能的关系。