Department of Ophthalmology, Military Institute of Medicine-National Research Institute, 128 Szaserow St., 04-141, Warsaw, Poland.
Department of Ophthalmology, Jozef Strus City Hospital, Poznan, Poland.
Sci Rep. 2024 Sep 30;14(1):22680. doi: 10.1038/s41598-024-66354-w.
The purpose was to evaluate the use of 3D CT-DCG-assisted and endoscopically guided coronary catheter balloon dacryoplasty (CC-BDCP) in adults with focal stenosis of the nasolacrimal duct (NLD) and report their long-term outcomes. A prospective, non-randomized, single-center clinical study was performed, and the patients underwent endoscopy-guided CC-BDCP using percutaneous transluminal coronary angioplasty (PTCA) balloon catheters. 25 patients were enrolled in the study. The CC-BDCP procedure was performed in 21 of 25 (84%) patients, and the remaining 4 (16%) patients had significant procedural difficulties due to unfavorable anatomical conditions. Of the 21 patients, 10 (47.6%) were procedurally assessed as "easy" (eCC-BDCP) and in 11 (52.4%) as procedurally "difficult" (dCC-BDCP). Values on Munk's epiphora intensity scale changed overall from 4.0 preoperatively to 1.4 ± 1.6 (p = 0.00001) postoperatively overall. FDDT changed overall from 2.9 ± 0.3 to 1.1 ± 1.2 after treatment (p = 0.00008) (from 2.8 ± 0.4 to 0.3 ± 0.6 in the eCC-BDCP group and from 2.9 ± 0.3 to 1.4 ± 1.2 in the dCC-BDCP group (p = 0.01352). The anatomical and functional success rate was 77% overall, 90% in the eCC-BDCP group, and 64% in the dCC-BDCP group. The CC-BDCP led to a statistically significant decrease in epiphora in a particular group of adult patients with demonstrable focal stenosis of the NLD.
目的是评估使用 3D CT-DCG 辅助和内窥镜引导的冠状动脉导管球囊泪道成形术（CC-BDCP）治疗鼻泪管（NLD）局灶性狭窄的成年人，并报告其长期结果。进行了一项前瞻性、非随机、单中心临床研究，患者接受经皮腔内冠状动脉成形术（PTCA）球囊导管内窥镜引导的 CC-BDCP。研究纳入 25 例患者。25 例患者中有 21 例（84%）进行了 CC-BDCP 手术，其余 4 例（16%）由于解剖条件不利，手术过程中出现明显困难。在 21 例患者中，10 例（47.6%）被评估为手术过程“简单”（eCC-BDCP），11 例（52.4%）为手术过程“困难”（dCC-BDCP）。Munk 溢泪强度量表的数值总体上从术前的 4.0 变为术后的 1.4±1.6（p=0.00001）。总体而言，FDDT 从治疗前的 2.9±0.3 变为 1.1±1.2（p=0.00008）（eCC-BDCP 组从 2.8±0.4 变为 0.3±0.6，dCC-BDCP 组从 2.9±0.3 变为 1.4±1.2）。总体解剖和功能成功率为 77%，eCC-BDCP 组为 90%，dCC-BDCP 组为 64%。CC-BDCP 导致特定组患有明显局灶性 NLD 狭窄的成年患者的溢泪症状在统计学上显著减少。
