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以恒定速度缓慢降低气管导管套囊压力可降低拔管期间的咳嗽发生率:一项随机临床试验。

Decreasing the pressure of endotracheal tube cuff slowly with a constant speed can decrease coughing incidence during extubation: a randomized clinical trial.

作者信息

Zhang Zhuan, Li Ning, Li Hu, Zhang Xinqi, Chen Chao, Yuan Bo, Wu Hao, Yu Yanlong

机构信息

Department of Anesthesiology, The Affiliated Hospital of Yangzhou University, Yangzhou University, No. 368 Hanjiang Road, Yangzhou, 225012, China.

Dalian Medical University, Dalian, 116000, China.

出版信息

Perioper Med (Lond). 2024 Sep 30;13(1):93. doi: 10.1186/s13741-024-00450-3.

Abstract

BACKGROUND

To discuss whether decreasing the pressure of endotracheal tube cuff slowly with a constant speed can decrease the incidence of coughing during extubation.

METHODS

Ninety patients undergoing elective noncardiac surgery under general anesthesia with endotracheal intubation were randomly divided into two groups: group P, the pilot balloon was connected to a syringe and an aneroid manometer through a three-way stopcock, respectively, and the decrease of cuff pressure was controlled at 3 cmHO/s during deflating before extubation; group C, the pressure in endotracheal tube cuff was decreased suddenly with a syringe extracting the air from the cuff rapidly at once exactly before extubation. The incidence of coughing during extubation period was recorded. Mean arterial pressure (MAP) and heart rate (HR) were recorded before general anesthesia induction (T0), just before cuff deflation (T1), immediately after deflation (T2), at 1 min (T3), 3 min (T4), and 5 min after extubation (T5). The occurrence of adverse reactions was also recorded.

RESULTS

The initiation of coughing during extubation period occurs at immediately the time of balloon deflation. Compared with group C, the incidence of coughing was significantly decreased (P = 0.001), MAP and HR were significantly decreased at T2-T4 and T2-T5, respectively (P < 0.05 for all), and the incidence of pharyngolaryngeal discomfort after extubation was significantly reduced (P = 0.021) in group P.

CONCLUSIONS

Decreasing the pressure of endotracheal tube cuff slowly with a constant speed can significantly reduce the incidence of coughing during extubating period, stabilize hemodynamics, and reduce the incidence of adverse reactions.

摘要

背景

探讨以恒定速度缓慢降低气管导管套囊压力是否能降低拔管期间咳嗽的发生率。

方法

90例接受全身麻醉下行择期非心脏手术并气管插管的患者被随机分为两组:P组,在拔管前放气时,将 Pilot 球囊分别通过三通旋塞连接到注射器和无液压力计上,套囊压力降低速度控制在3 cmH₂O/s;C组,在拔管前瞬间用注射器迅速抽出套囊内空气,使气管导管套囊压力突然降低。记录拔管期间咳嗽的发生率。记录全身麻醉诱导前(T0)、套囊放气前即刻(T1)、放气后即刻(T2)、拔管后1分钟(T3)、3分钟(T4)和5分钟(T5)时的平均动脉压(MAP)和心率(HR)。同时记录不良反应的发生情况。

结果

拔管期间咳嗽在套囊放气瞬间开始出现。与C组相比,P组咳嗽发生率显著降低(P = 0.001),T2 - T4时MAP显著降低,T2 - T5时HR显著降低(均P < 0.05),P组拔管后咽喉部不适发生率显著降低(P = 0.021)。

结论

以恒定速度缓慢降低气管导管套囊压力可显著降低拔管期间咳嗽的发生率,稳定血流动力学,并降低不良反应的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39b0/11441075/784d32067b03/13741_2024_450_Fig1_HTML.jpg

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