Angel C Y, Vuthien H, Letienne G, Pernes J M, Brenot P, Parola J L, Raynaud A, Gaux J C
Arch Mal Coeur Vaiss. 1985 Aug;78(8):1174-80.
Digitalisation enables angiocardiography to be performed by a peripheral intravenous injection. Computer-assisted analysis of the date widens the possibilities of quantification. The authors have developed a videodensitometric method of studying the left ventricular ejection fraction. The research was performed on an experimental model and the technique validated in a series of 10 patients. The experimental model consisted of a series of balloons which, when inflated with contrast medium assumed an allipsoid shape resembling a left ventricle. The balloons were blown up in two stages with an automatic injector to simulate systole and diastole. The images were recorded in the same way as during ventriculography. Videodensitometric measurements showed 3 to 5% variations from the true values. The method was then applied to the calculation of the left ventricular ejection fraction in 10 patients: left ventricular function was also quantified by geometrical methods (Dodge) from the same angiogrammes and the 2 sets of results were then compared. The correlation coefficient between the two methods was 0.97, so validating the new technique. Videodensitometry opens up new perspectives in the study of left ventricular function. On the other hand it can be used to monitor the ejection fraction in severely ill or recently operated patients, and, on the other hand the principle of videodensitometry eliminates the geometrical approximations inherent in the classical methods of angiographic analysis and would therefore seem to be more suitable for the study of pathological left ventricules (aneurysm...). Finally, the technique of videodensitometry represents a new step towards the measurement of true volumes and flow rates.
数字化使得通过外周静脉注射进行心血管造影成为可能。对数据的计算机辅助分析拓宽了量化的可能性。作者们开发了一种研究左心室射血分数的视频密度测定法。该研究在一个实验模型上进行，并在一系列10名患者中对该技术进行了验证。实验模型由一系列气球组成，当用造影剂充气时，它们呈现出类似左心室的椭球体形状。气球通过自动注射器分两个阶段充气，以模拟收缩期和舒张期。图像的记录方式与心室造影时相同。视频密度测定结果显示与真实值有3%至5%的差异。然后将该方法应用于10名患者左心室射血分数的计算：左心室功能也通过几何方法（道奇法）从相同的血管造影片中进行量化，然后将两组结果进行比较。两种方法之间的相关系数为0.97，从而验证了这项新技术。视频密度测定法为左心室功能的研究开辟了新的前景。另一方面，它可用于监测重症患者或近期手术患者的射血分数，而且，视频密度测定法的原理消除了传统血管造影分析方法中固有的几何近似，因此似乎更适合于研究病理性左心室（动脉瘤……）。最后，视频密度测定技术代表了朝着测量真实容积和流速迈出的新一步。
