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新生儿胸骨裂的管理与手术修复:两例成功干预的病例报告

Management and Surgical Repair of Neonatal Sternal Cleft: A Case Report of Two Successful Interventions.

作者信息

Khan Muhammad Taimour, Amjad Ibrahim, Khan Muhammad Rahab

机构信息

Internal Medicine, Institute of Dentistry, CMH Lahore Medical College, Lahore, PAK.

Plastic Surgery, AmjadPlastics, Miami, USA.

出版信息

Cureus. 2024 Aug 31;16(8):e68327. doi: 10.7759/cureus.68327. eCollection 2024 Aug.

DOI:10.7759/cureus.68327
PMID:39350810
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11442012/
Abstract

The sternal cleft (SC) is a rare congenital anomaly characterized by a complete or partial separation of the sternum, leading to significant clinical concerns, including respiratory and cardiac instability. Due to its rarity, the SC often poses surgical challenges. This case report highlights the management of two neonates with SCs, emphasizing the critical role of early multidisciplinary intervention. The first patient, a neonate, was born with a severe sternal deformity identified as a partial superior SC with a supraumbilical raphe. The patient was transported to a tertiary care center for further evaluation and management by a multidisciplinary team. Similarly, the second patient, another neonate, presented with similar sternal changes. Both patients were assessed for potential complications associated with sternal instability. The treatment involved surgical correction by closing the gap of the SC for both patients. The procedure included a midline skin incision, dissection and lateral reflection of the pectoralis major muscle, resection of cartilaginous plates for healthy cartilage fusion, and extension of the cleft through the manubrium to achieve anatomic closure by approximation and suturing. Intraoperative monitoring ensured the stability of cardiac and respiratory functions. Postoperative outcomes were favorable, with both patients recovering well and being discharged without complications on postoperative days 5 and 9. These cases highlight the significance of early surgical intervention with multidisciplinary management in neonates with SCs. The successful outcomes underscore the effectiveness of surgical intervention in preventing possible complications, ensuring rapid recovery, and stabilizing the chest. Further research into long-term outcomes and potential genetic factors may provide deeper insights into the management of this rare condition.

摘要

胸骨裂(SC)是一种罕见的先天性异常,其特征为胸骨完全或部分分离,导致包括呼吸和心脏功能不稳定在内的重大临床问题。由于其罕见性,胸骨裂常常带来手术挑战。本病例报告重点介绍了两名患有胸骨裂的新生儿的治疗情况,强调了早期多学科干预的关键作用。第一名患者为一名新生儿,出生时伴有严重的胸骨畸形,被诊断为部分上胸骨裂并伴有脐上缝。该患者被转运至三级医疗中心,由多学科团队进行进一步评估和治疗。同样,第二名患者也是一名新生儿,呈现出类似的胸骨变化。对两名患者都评估了与胸骨不稳定相关的潜在并发症。治疗方法包括通过闭合两名患者的胸骨裂间隙进行手术矫正。手术步骤包括沿中线做皮肤切口,解剖并向外侧翻转胸大肌,切除软骨板以实现健康软骨融合,通过胸骨柄延长裂隙以通过近似和缝合实现解剖学闭合。术中监测确保了心脏和呼吸功能的稳定。术后结果良好,两名患者恢复良好,分别在术后第5天和第9天无并发症出院。这些病例突出了对患有胸骨裂的新生儿进行早期手术干预和多学科管理的重要性。成功的结果强调了手术干预在预防可能的并发症、确保快速康复和稳定胸部方面的有效性。对长期结果和潜在遗传因素的进一步研究可能会为这种罕见病症的治疗提供更深入的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/5b3d816969a6/cureus-0016-00000068327-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/bd37f01ba63b/cureus-0016-00000068327-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/f5aad162ca56/cureus-0016-00000068327-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/4fb7373ccace/cureus-0016-00000068327-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/c2988214a43b/cureus-0016-00000068327-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/2b53e50aa91a/cureus-0016-00000068327-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/327c8444d772/cureus-0016-00000068327-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/0aa7b932b5b9/cureus-0016-00000068327-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/ecbf4bf33202/cureus-0016-00000068327-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/393468c04742/cureus-0016-00000068327-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/5b3d816969a6/cureus-0016-00000068327-i10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/bd37f01ba63b/cureus-0016-00000068327-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/f5aad162ca56/cureus-0016-00000068327-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/4fb7373ccace/cureus-0016-00000068327-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/c2988214a43b/cureus-0016-00000068327-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/2b53e50aa91a/cureus-0016-00000068327-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/327c8444d772/cureus-0016-00000068327-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/0aa7b932b5b9/cureus-0016-00000068327-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/ecbf4bf33202/cureus-0016-00000068327-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/393468c04742/cureus-0016-00000068327-i09.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b58f/11442012/5b3d816969a6/cureus-0016-00000068327-i10.jpg

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本文引用的文献

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Isolated central sterna clefts: A rare congenital malformation.孤立性中央胸骨裂:一种罕见的先天性畸形。
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Reconstruction of Congenital Sternal Cleft: A Systematic Review of the Literature.先天性胸骨裂的重建:文献系统综述。
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