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本文引用的文献

1
Thromboembolic complications in burn patients and associated risk factors.烧伤患者的血栓栓塞并发症及相关危险因素
J Burn Care Res. 2013 May-Jun;34(3):355-60. doi: 10.1097/BCR.0b013e31827819a1.
2
Venous thromboembolism in thermally injured patients: analysis of the National Burn Repository.热损伤患者的静脉血栓栓塞:国家烧伤资料库分析
J Burn Care Res. 2011 Jan-Feb;32(1):6-12. doi: 10.1097/BCR.0b013e318204b2ff.
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Global evacuation of burn patients does not increase the incidence of venous thromboembolic complications.
J Trauma. 2008 Jul;65(1):19-24. doi: 10.1097/TA.0b013e3181271b8a.
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Prevention of venous thromboembolism: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition).静脉血栓栓塞的预防:美国胸科医师学会循证临床实践指南(第8版)
Chest. 2008 Jun;133(6 Suppl):381S-453S. doi: 10.1378/chest.08-0656.
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[Venous thromboprophylaxis in burn patient].[烧伤患者的静脉血栓预防]
Ann Fr Anesth Reanim. 2005 Aug;24(8):947-50. doi: 10.1016/j.annfar.2005.05.008.
6
Analysis of deep vein thrombosis in burn patients.烧伤患者深静脉血栓形成的分析
Burns. 2004 Sep;30(6):591-3. doi: 10.1016/j.burns.2003.12.019.
7
The prevalence of venous thromboembolism of the lower extremity among thermally injured patients determined by duplex sonography.通过双功超声检查确定热损伤患者下肢静脉血栓栓塞的患病率。
J Trauma. 2003 Dec;55(6):1162-7. doi: 10.1097/01.TA.0000057149.42968.1D.
8
Venous thrombosis and pulmonary embolism. A clinico-pathological study in injured and burned patients.静脉血栓形成与肺栓塞。一项针对受伤及烧伤患者的临床病理研究。
Br J Surg. 1961 Mar;48:475-89. doi: 10.1002/bjs.18004821103.
9
[Deep vein thrombosis in a burn patient].[一名烧伤患者的深静脉血栓形成]
Rev Med Liege. 2002 Sep;57(9):587-90.
10
Venous thrombosis incidence in burn patients: preliminary results of a prospective study.烧伤患者静脉血栓形成的发生率:一项前瞻性研究的初步结果。
J Burn Care Rehabil. 2002 Mar-Apr;23(2):97-102. doi: 10.1097/00004630-200203000-00005.

[烧伤患者的静脉血栓栓塞症:发病率及危险因素]

[VENOUS THROMBO-EMBOLISM IN BURNS: INCIDENCE AND RISK FACTORS].

作者信息

Ben Khalifa H, Mokline A, Fraj H, Zarrouk S, Eljemi I, Gasri B, Ben Saad M, Messadi A A

机构信息

Université de Tunis El Manar, Faculté de Médecine de Tunis, Tunisie.

Service de Réanimation des Brûlés, Centre de Traumatologie et des Grands Brûlés, Tunis, Tunisie.

出版信息

Ann Burns Fire Disasters. 2024 Sep 30;37(3):233-237. eCollection 2024 Sep.

PMID:39350889
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11372277/
Abstract

Venous thromboembolic disease (VTE) in burn patients is an under-diagnosed and potentially serious complication. Its incidence varies according to studies performed. This retrospective and descriptive study conducted in an intensive burn care department in Tunisia over a period of 22 months (January 1, 2021 to October 30, 2022) included 24 patients who presented a thromboembolic complication among a total of 785 admissions (incidence of 3%): pulmonary embolism in 15 cases and deep venous thrombosis (DVT) in 9 cases. The mean age of the patients was 43.8 years, with a male:female sex ratio of 2:1. Two thirds of patients (n=17) had a pathological history: hypertension (n=3); diabetes (n=2) and neoplasia (n=2). Three patients were obese. The average TBSA was 29%. Burns involved lower limbs in 19 patients (79%). The mean time to onset of VTE was 27.8 days. Acute dyspnea was present in 1/2 of cases and tachycardia in 1/3 of cases. The association hypoxia-hypocapnia was found in 5 patients. The diagnosis was confirmed by: thoracic angioscan (n=14), pulmonary scintigraphy (n=1), venous Doppler ultrasound of the lower limbs (n=2) and phleboscan of lower limbs (n=7). Factors correlated with thromboembolic risk in our study were: TBSA 20% - 39% (p=0,029; RR=4), with lower limb involvement (p=0,068), catheterization duration ≥7 days (p=0,048; RR=3) and number of catheters >1 (p=0,01; RR=3). The outcome was favorable in 13 patients and fatal in 11 patients.

摘要

烧伤患者的静脉血栓栓塞性疾病(VTE)是一种诊断不足且可能严重的并发症。其发病率因所开展的研究而异。这项在突尼斯一家重症烧伤护理科进行的回顾性描述性研究,历时22个月(2021年1月1日至2022年10月30日),纳入了785例住院患者中出现血栓栓塞并发症的24例患者(发病率为3%):15例发生肺栓塞,9例发生深静脉血栓形成(DVT)。患者的平均年龄为43.8岁,男女比例为2:1。三分之二的患者(n = 17)有病史:高血压(n = 3);糖尿病(n = 2)和肿瘤(n = 2)。3例患者肥胖。平均烧伤总面积为29%。19例患者(79%)的烧伤累及下肢。VTE发病的平均时间为27.8天。半数病例出现急性呼吸困难,三分之一病例出现心动过速。5例患者存在低氧血症 - 低碳酸血症。诊断通过以下方式得以证实:胸部血管扫描(n = 14)、肺闪烁扫描(n = 1)、下肢静脉多普勒超声(n = 2)和下肢静脉造影(n = 7)。在我们的研究中,与血栓栓塞风险相关的因素有:烧伤总面积20% - 39%(p = 0.029;相对危险度 = 4)、累及下肢(p = 0.068)、置管时间≥7天(p = 0.048;相对危险度 = 3)以及导管数量>1(p = 0.01;相对危险度 = 3)。13例患者预后良好,11例患者死亡。