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使用细胞骨移植增强技术进行后足和踝关节融合术后的临床及影像学结果:一篇简短报告。

Clinical and Radiographic Outcomes After Hindfoot and Ankle Arthrodesis Using Cellular Bone Allograft Augmentation: A Short Report.

作者信息

Ruland Jeffrey R, Sumpter Anna, McVey Eric, Novicoff Wendy, Pierce Jennifer, Cooper Minton T, Perumal Venkat, Park Joseph S

机构信息

Department of Orthopaedic Surgery, University of Virginia, Charlottesville, VA, USA.

Department of Radiology, University of Virginia, Charlottesville, VA, USA.

出版信息

Foot Ankle Orthop. 2024 Sep 30;9(3):24730114241281325. doi: 10.1177/24730114241281325. eCollection 2024 Jul.

Abstract

BACKGROUND

Nonunion after ankle or hindfoot arthrodesis is associated with poor outcomes. Cellular bone allograft is an alternative to autograft for use in these procedures. The purpose of this study was to prospectively evaluate the early efficacy and safety of cellular bone allograft use in hindfoot and ankle arthrodesis procedures.

METHODS

Fourteen patients undergoing hindfoot or ankle arthrodesis supplemented with cellular bone allograft were prospectively enrolled. Computed tomography (CT) scans were obtained postoperatively at set time points and reviewed by 3 fellowship-trained foot and ankle surgeons as well as 1 musculoskeletal radiologist. Primary outcome was CT-verified union, defined as >25% of joint surface. Complications were recorded and revision procedures offered as indicated.

RESULTS

CT-verified union rate during the study period was 76.7% (23 of 30 joints). Union was 100% for the ankle joint (2 of 2), 50% for the talonavicular joint (5 of 10), 100% for the calcaneocuboid joint (8 of 8), and 80.0% for the subtalar joint (8 of 10). One patient underwent revision fusion procedure, and 1 patient underwent hardware removal during the study period.

CONCLUSION

Our initial experience suggests that use of cellular bone allograft augmentation in hindfoot and ankle arthrodesis may offer an alternative to autograft without potential of donor site morbidity.

LEVEL OF EVIDENCE

Level IV, case series.

摘要

背景

踝关节或后足关节融合术后骨不连与不良预后相关。在这些手术中,细胞骨移植是自体骨移植的一种替代方法。本研究的目的是前瞻性评估细胞骨移植在后足和踝关节融合手术中的早期疗效和安全性。

方法

前瞻性纳入14例行后足或踝关节融合并补充细胞骨移植的患者。术后在设定时间点进行计算机断层扫描(CT),并由3名接受过专科培训的足踝外科医生和1名肌肉骨骼放射科医生进行评估。主要结局是CT证实的骨愈合,定义为关节面的25%以上。记录并发症,并根据需要提供翻修手术。

结果

研究期间CT证实的骨愈合率为76.7%(30个关节中的23个)。踝关节的骨愈合率为100%(2个中的2个),距舟关节为50%(10个中的5个),跟骰关节为100%(8个中的8个),距下关节为80.0%(10个中的8个)。1例患者在研究期间接受了翻修融合手术,1例患者接受了内固定取出术。

结论

我们的初步经验表明,在后足和踝关节融合术中使用细胞骨移植增强可能是自体骨移植的一种替代方法,且无供区并发症的风险。

证据水平

IV级,病例系列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a652/11440521/a44b277d35e1/10.1177_24730114241281325-fig1.jpg

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