Dr Fahmida Yeasmin, Lecturer, Department of Physiology, Mymensingh Medical College (MMC), Mymensingh, Bangladesh; E-mail:
Mymensingh Med J. 2024 Oct;33(4):1054-1057.
Sedentary behavior has significant deleterious effects on human health. Sedentary behaviors associated with cardiovascular and metabolic disorders by decreasing lipoprotein lipase activities, impaired lipid and carbohydrate metabolism. This cross sectional study was done to see the association between fasting serum glucose and serum total cholesterol in sedentary male. This study was conducted in the Department of Physiology, Mymensingh Medical College, Bangladesh from Octy 2021 to June 2022. A total number of 100 subjects were included in this study. Among them, fifty (50) sedentary males were taken as study group (Group II) and fifty (50) active males were taken as control group (Group I). Age of both control and study group ranged from 25-60 years. Data were expressed as mean±SD and statistical significance of difference among the group was calculated by unpaired students' 't' test & Pearson's correlation coefficient test. Both of these biochemical parameters showed statistically significant difference in study group. The mean±SD of fasting serum glucose of control group (Group I) and study group (Group II) were 4.45±0.51 mmol/L and 5.91±0.60 mmol/L; and the mean±SD of serum total cholesterol level of control group (Group I) and study group (Group II) were 176.14±27.16 mg/dl and 252.58±18.97 mg/dl respectively. Fasting serum glucose and serum total cholesterol shows positive correlation in study group in comparison to control group. From this finding it can be concluded that there was significant correlation of fasting serum glucose and serum total cholesterol in sedentary males.
久坐行为对人类健康有显著的有害影响。与心血管和代谢紊乱相关的久坐行为通过降低脂蛋白脂肪酶活性、损害脂质和碳水化合物代谢来发挥作用。本横断面研究旨在观察久坐男性空腹血清葡萄糖与血清总胆固醇之间的关系。本研究于 2021 年 10 月至 2022 年 6 月在孟加拉国迈门辛医学院生理学系进行。本研究共纳入 100 例受试者,其中 50 例久坐男性为研究组(II 组),50 例活跃男性为对照组(I 组)。对照组和研究组的年龄均在 25-60 岁之间。数据表示为均值±标准差,组间差异的统计学意义采用配对学生“t”检验和 Pearson 相关系数检验进行计算。这两个生化参数在研究组中均显示出统计学上的显著差异。对照组(I 组)和研究组(II 组)的空腹血清葡萄糖均值±标准差分别为 4.45±0.51mmol/L 和 5.91±0.60mmol/L;对照组(I 组)和研究组(II 组)的血清总胆固醇水平均值±标准差分别为 176.14±27.16mg/dl 和 252.58±18.97mg/dl。与对照组相比,研究组空腹血清葡萄糖和血清总胆固醇呈正相关。从这一发现可以得出结论,在久坐男性中,空腹血清葡萄糖和血清总胆固醇之间存在显著相关性。