为了更好地理解慢性乙型肝炎病毒感染。 - Suppr

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超能文献

Toward a better understanding of chronic hepatitis B virus infection.

作者信息

Rehermann Barbara

出版信息

J Clin Invest. 2024 Oct 1;134(19):e185568. doi: 10.1172/JCI185568.

DOI:10.1172/JCI185568

PMID:39352391

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11444154/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/022a/11444154/b425edaa5545/jci-134-185568-g130.jpg

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本文引用的文献

A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.肝脏免疫调节装置调控慢性乙型肝炎病毒感染中的 CD8 T 细胞免疫。

Nature. 2024 Jul;631(8022):867-875. doi: 10.1038/s41586-024-07630-7. Epub 2024 Jul 10.

Structural conservation of HBV-like capsid proteins over hundreds of millions of years despite the shift from non-enveloped to enveloped life-style.尽管从非包膜生活方式转变为包膜生活方式，但乙型肝炎病毒样衣壳蛋白在数亿年中保持结构保守。

Nat Commun. 2023 Mar 22;14(1):1574. doi: 10.1038/s41467-023-37068-w.

Deregulated intracellular pathways define novel molecular targets for HBV-specific CD8 T cell reconstitution in chronic hepatitis B.肝细胞内通路失调定义了慢性乙型肝炎中乙型肝炎病毒特异性 CD8 T 细胞重建的新的分子靶点。

J Hepatol. 2023 Jul;79(1):50-60. doi: 10.1016/j.jhep.2023.02.035. Epub 2023 Mar 7.

The scientific basis of combination therapy for chronic hepatitis B functional cure.慢性乙型肝炎功能性治愈联合治疗的科学依据。

Nat Rev Gastroenterol Hepatol. 2023 Apr;20(4):238-253. doi: 10.1038/s41575-022-00724-5. Epub 2023 Jan 11.

Functional cure of hepatitis B requires silencing covalently closed circular and integrated hepatitis B virus DNA.功能性治愈乙型肝炎需要沉默共价闭合环状和整合乙型肝炎病毒 DNA。

J Clin Invest. 2022 Sep 15;132(18):e163175. doi: 10.1172/JCI163175.

Integrated hepatitis B virus DNA maintains surface antigen production during antiviral treatment.整合的乙型肝炎病毒 DNA 在抗病毒治疗期间维持表面抗原的产生。

J Clin Invest. 2022 Sep 15;132(18). doi: 10.1172/JCI161818.

Origins and Evolution of the Primate Hepatitis B Virus.灵长类动物乙型肝炎病毒的起源与进化

Front Microbiol. 2021 May 24;12:653684. doi: 10.3389/fmicb.2021.653684. eCollection 2021.

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Sci Transl Med. 2021 Mar 31;13(587). doi: 10.1126/scitranslmed.aba6322.

Hepatitis B virus integrations promote local and distant oncogenic driver alterations in hepatocellular carcinoma.乙型肝炎病毒整合促进肝细胞癌中局部和远处致癌驱动基因的改变。

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