Li Shu Hua, Shan Xiu Juan, Wang Zhen Hua, Tao Shu Jie
Department of Dermatology and Plastic Surgery, Hospital of Weifang People, the Second Medical University of Shandong.
Shandong Key Laboratory of Medicine, Health and Skin immunity, Hospital of Weifang People, the Second Medical University of Shandong, Shandong, China.
J Craniofac Surg. 2024 Oct 1;35(8):2386-9. doi: 10.1097/SCS.0000000000010649.
Ear keloids are pathologic scar hyperplasia in the ear region. The most therapeutic approach was surgical shave excision with radiation therapy. However, radiation therapy is easily delivered to healthy surrounding tissues. In the last years, injections with botulinum toxin type A (BTX-A) have been proven to improve surgical scars effectively in clinical trials. This study aimed to evaluate the effect of immediate injections of BTX-A after surgical excision for ear keloids.
From January 2020 to January 2023, 33 consecutive patients with ear keloids were enrolled. All patients underwent scar excision and revision at the same time when they needed BTX-A. It was injected into surgical wound closure immediately after surgery. The results of this study were evaluated at follow-up from 7 to 18 months using the Vancouver Scar Scale (VSS) and the Visual Analogue Scale (VAS).
From January 2020 to January 2023, 33 patients received concomitant therapy of immediate injections of BTX-A after surgery for ear keloids. The patients were evaluated at follow-ups lasting 7 to 18 months. Only one case recurred within the follow-up period, and no adverse effects were reported.
This study demonstrates that significant cosmetic outcomes in ear keloid treatment were achieved after early postsurgical BTX-A injections. The patients reported high satisfaction and few complications.
耳部瘢痕疙瘩是耳部区域的病理性瘢痕增生。最常用的治疗方法是手术刮除切除联合放射治疗。然而，放射治疗容易对周围健康组织造成损伤。近年来，A型肉毒杆菌毒素（BTX-A）注射已被证明在临床试验中能有效改善手术瘢痕。本研究旨在评估耳部瘢痕疙瘩手术切除后立即注射BTX-A的效果。
2020年1月至2023年1月，连续纳入33例耳部瘢痕疙瘩患者。所有患者在需要BTX-A治疗时同时进行瘢痕切除和修复手术。术后立即将其注射到手术伤口闭合处。本研究结果在7至18个月的随访中使用温哥华瘢痕量表（VSS）和视觉模拟量表（VAS）进行评估。
2020年1月至2023年1月，33例患者接受了耳部瘢痕疙瘩手术后立即注射BTX-A的联合治疗。患者在持续7至18个月的随访中接受评估。随访期间仅1例复发，未报告不良反应。
本研究表明，耳部瘢痕疙瘩手术后早期注射BTX-A可取得显著的美容效果。患者满意度高，并发症少。
