Siberian State Medical University, Ministry of Health of the Russian Federation, Tomsk, Russia.
Seversk Biophysical Research Center, Federal Medical-Biological Agency of Russia, Seversk, Russia.
Bull Exp Biol Med. 2024 Sep;177(5):673-677. doi: 10.1007/s10517-024-06247-0. Epub 2024 Oct 1.
The structure of left ventricular cardiomyocytes of 1 day preterm newborn rats was studied using transmission electron microscopy. It was shown that the relative area of the nucleus in cardiomyocytes of preterm rats is lower, and the relative area of the cytoplasm is higher than in full-term rats, while the relative areas of myofibrils and mitochondria do not differ. In cardiomyocytes of preterm rats damaged mitochondria, subsegmental myofibrillar contracture, and cytoplasmic swelling were found on the first postnatal day. Preterm birth in rats, in contrast to birth at term, is accompanied by the development of a number of ultrastructural damages in cardiomyocytes.
采用透射电子显微镜研究了 1 日龄早产新生大鼠左心室心肌细胞的结构。结果表明，早产大鼠心肌细胞的细胞核相对面积较低，细胞质相对面积较高，而肌原纤维和线粒体的相对面积则没有差异。在出生后第一天的早产大鼠心肌细胞中发现受损的线粒体、亚段肌原纤维收缩和细胞质肿胀。与足月出生相比，大鼠早产会伴随着心肌细胞发生一系列超微结构损伤。
