Gou Fei, Wang Qiuting, Yang Zihong, Chang Wenju, Shen Jie, Zeng Huaqiang
College of Chemistry, Fuzhou University, Fuzhou, Fujian 350116, China.
Angew Chem Int Ed Engl. 2025 Feb 10;64(7):e202418304. doi: 10.1002/anie.202418304. Epub 2024 Nov 7.
In sharp contrast to numerous artificial potassium channels developed over the past decade, the study of artificial lithium-transporting channels has remained limited. We demonstrate here the use of an interesting class of polymers with intrinsic microporosity (PIM) for constructing artificial lithium channels. These PIM-derived lithium channels show exceptionally efficient (γ >40 pS) and highly selective transport of Li ions, with selectivity factors of>10 against both Na and K. By simply adjusting the initial reaction temperature, we can tune the transport property in a way that PIMs synthesized at initial reaction temperatures of 60 °C and 80 °C exhibit improved transport efficiency and selectivity, respectively, in the dioleoyl phosphatidylcholine membrane.
与过去十年开发的众多人工钾通道形成鲜明对比的是，人工锂转运通道的研究仍然有限。我们在此展示了使用一类有趣的具有固有微孔性的聚合物（PIM）来构建人工锂通道。这些源自PIM的锂通道显示出异常高效（γ>40 pS）且对锂离子具有高度选择性的转运，对Na和K的选择性因子均>10。通过简单地调整初始反应温度，我们可以以一种方式调节转运特性，即在60°C和80°C的初始反应温度下合成的PIM分别在二油酰磷脂酰胆碱膜中表现出提高的转运效率和选择性。
