College of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, China.
School of Naval Architecture and Maritime, Zhejiang Ocean University, Zhoushan, China.
Food Chem. 2025 Jan 15;463(Pt 4):141428. doi: 10.1016/j.foodchem.2024.141428. Epub 2024 Sep 25.
Astaxanthin (AST) exhibits potent antioxidant activity, effectively preventing neurological diseases and cancer. Presently, producing AST from microorganisms like Haematococcus pluvialis and Phaffia rhodozyma is a growing trend. This review summarizes the main research topics on AST in the past five years. AST plays a crucial role in cancer and diabetes prevention, as well as neuroprotection, however, the presence of both free and esterified forms of AST results in differences in their functionality and applications. The primary challenges in industrial production of natural AST lie in breeding high-yield natural producers and developing methods to enhance yield. The use of high-quality food matrix materials and preparation methods is crucial for the delivery system of loaded AST. This study elucidates the bottlenecks and future development directions encountered by natural AST during industrialization, aiming to promote the healthy and rapid growth of the food industry.
虾青素（AST）具有很强的抗氧化活性，可有效预防神经退行性疾病和癌症。目前，从雨生红球藻和红发夫酵母等微生物中生产 AST 是一个日益增长的趋势。本文综述了过去五年中 AST 的主要研究课题。AST 在预防癌症和糖尿病以及神经保护方面发挥着重要作用，但由于 AST 既存在游离形式又存在酯化形式，导致其功能和应用存在差异。在天然 AST 的工业生产中，主要的挑战在于培育高产天然生产菌和开发提高产量的方法。使用高质量的食品基质材料和制备方法对于负载 AST 的递送系统至关重要。本研究阐明了天然 AST 在工业化过程中遇到的瓶颈和未来发展方向，旨在促进食品工业的健康快速发展。
