Santos-de-Araújo Aldair Darlan, Bassi-Dibai Daniela, Dourado Izadora Moraes, Marinho Renan Shida, Mendes Renata Gonçalves, da Luz Goulart Cássia, Batista Dos Santos Polliana, Roscani Meliza Goi, Phillips Shane A, Arena Ross, Borghi-Silva Audrey
Cardiopulmonary Physiotherapy Laboratory, Universidade Federal de São Carlos, Federal University of Sao Carlos Rodovia Washington Luiz, São Carlos, 13565-905, SP, Brazil.
Management in Health Programs and Services, Universidade CEUMA, São Luís, MA, Brazil.
BMC Cardiovasc Disord. 2024 Oct 1;24(1):530. doi: 10.1186/s12872-024-04218-x.
The Duke Activity Status Index (DASI) questionnaire has been the focus of numerous investigations - its discriminative and prognostic capacity has been continuously explored, supporting its use in the clinical setting, specifically during rehabilitation in patients with chronic heart failure (CHF).However, studies exploring optimal DASI questionnaire threshold scores are limited.
To investigate optimal DASI questionnaire thresholds values in predicting mortality in a CHF cohort and assess mortality rates based on the DASI questionnaire using a thresholds values obtained.
This is a prospective cohort study with a 36-month follow-up in patients with CHF. All patients completed a clinical assessment, followed by DASI questionnaire, pulmonary function, and echocardiography. The Receiver Operating Characteristic (ROC) curve analysis was used to discriminate the DASI questionnaire score in determining the risk of mortality. For survival analysis, the Kaplan-Meier model was used to explore the impact of ≤/>23 points on mortality occurring during the 36-month follow-up.
One hundred and twenty-four patients were included, the majority being elderly men. Kaplan Meier analysis revealed that ≤/> 23 was a strong predictor of CHF mortality over a 36-month follow-up.
A score of ≤/>23 presents good discriminatory capacity to predict mortality risk in 36 months in patients with CHF, especially in those with reduced or mildly reduced ejection fraction. Age, ejection fraction, DASI questionnaire score and use of digoxin are risk factors that influence mortality in this population.
杜克活动状态指数（DASI）问卷一直是众多研究的焦点——其鉴别和预后能力不断得到探索，这支持了它在临床环境中的应用，特别是在慢性心力衰竭（CHF）患者的康复过程中。然而，探索DASI问卷最佳阈值分数的研究有限。
调查DASI问卷在预测CHF队列死亡率方面的最佳阈值，并使用获得的阈值基于DASI问卷评估死亡率。
这是一项对CHF患者进行36个月随访的前瞻性队列研究。所有患者均完成临床评估，随后进行DASI问卷、肺功能和超声心动图检查。采用受试者操作特征（ROC）曲线分析来鉴别DASI问卷分数在确定死亡风险方面的作用。对于生存分析，使用Kaplan-Meier模型来探讨≤/＞23分对36个月随访期间发生的死亡率的影响。
纳入124例患者，大多数为老年男性。Kaplan-Meier分析显示，在36个月的随访中，≤/＞23分是CHF死亡率的有力预测指标。
≤/＞23分在预测CHF患者36个月内的死亡风险方面具有良好的鉴别能力，尤其是在射血分数降低或轻度降低的患者中。年龄、射血分数、DASI问卷分数和地高辛的使用是影响该人群死亡率的危险因素。
