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多原发性双侧肺结节同期双侧单孔胸腔镜手术的回顾性分析

A retrospective analysis of simultaneous bilateral uniportal thoracoscopic surgeries for multiple primary bilateral pulmonary nodules.

作者信息

Zhou Jun-Jun, Song Xiao-Yong, Huang Bing-Yang, Zhang Xiao-Wei, Shao Jia-Feng, Li Lu, Meng Yong-Sheng

机构信息

Department of Thoracic Surgery, The Ninth Medical Center of PLA General Hospital, No. 9 Anxiang North Lane, Deshengmenwai, Chaoyang District, Beijing, 100101, China.

出版信息

J Cardiothorac Surg. 2024 Oct 1;19(1):566. doi: 10.1186/s13019-024-03051-9.

Abstract

BACKGROUND

There are no standard treatment options for bilateral multiple pulmonary nodules requiring resection. This study aimed to summarize the experience of simultaneous bilateral uniportal video-assisted thoracoscopic surgery for the treatment of bilateral multiple primary pulmonary nodules.

METHODS

The clinical data of 65 cases of simultaneous bilateral uniportal thoracoscopic surgery for bilateral multiple primary pulmonary nodules treated were retrospectively analyzed. These cases were treated within The Ninth Medical Center of PLA General Hospital between January 2018 and November 2020. Parameters related to the surgery, perioperative aspects, surgical techniques, pathology results, and postoperative complications were examined.

RESULTS

All surgeries were conducted through uniportal video-assisted thoracoscopic surgery, with no instances of intraoperative conversion to thoracotomy. Fifty-three patients further underwent CT-guided Hookwire localization for the localization of pulmonary nodules. A total of 189 nodules were resected using multiple surgical procedures, with a malignancy rate of 86.2%. The average operation time was 226 ± 77.4 min, the average thoracic drainage duration was 3.1 ± 1.5 days, the average 24 h pleural drainage was 385.9 ± 157.4 mL, the average postoperative hospital stay was 8.6 ± 2.4 days, and the average blood loss was 77.2 ± 33.8 mL. Post-surgery, all patients were transferred to the ward safely within 12 h. 15.38% of patients have prolonged drainage time, and 12.31% of patients experience complications such as lung infection, arrhythmia, and venous thrombosis.

CONCLUSION

The selected cases undergoing simultaneous bilateral uniportal video-assisted thoracoscopic surgery for the management of bilateral multiple primary pulmonary nodules demonstrated favorable outcomes. Our observations indicate the safety and feasibility of this procedure, providing an individualized and precise treatment approach for affected patients.

摘要

背景

对于需要切除的双侧多发性肺结节,目前尚无标准的治疗方案。本研究旨在总结同期双侧单孔电视辅助胸腔镜手术治疗双侧多发性原发性肺结节的经验。

方法

回顾性分析2018年1月至2020年11月在解放军总医院第九医学中心接受同期双侧单孔胸腔镜手术治疗的65例双侧多发性原发性肺结节患者的临床资料。检查与手术、围手术期情况、手术技术、病理结果及术后并发症相关的参数。

结果

所有手术均通过单孔电视辅助胸腔镜手术完成,无术中转为开胸手术的情况。53例患者进一步接受了CT引导下Hookwire定位以明确肺结节位置。共采用多种手术方式切除189个结节,恶性率为86.2%。平均手术时间为226±77.4分钟,平均胸腔引流时间为3.1±1.5天,平均24小时胸腔引流量为385.9±157.4毫升,平均术后住院时间为8.6±2.4天,平均失血量为77.2±33.8毫升。术后所有患者均在12小时内安全转入病房。15.38%的患者引流时间延长,12.31%的患者出现肺部感染、心律失常和静脉血栓形成等并发症。

结论

所选同期双侧单孔电视辅助胸腔镜手术治疗双侧多发性原发性肺结节的病例显示出良好的效果。我们的观察表明该手术具有安全性和可行性,为受影响患者提供了个体化和精确的治疗方法。

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