在超过1500例连续患者中，与传统静脉移植物相比，非接触式静脉移植物具有更好的长期通畅率。
Superior long-term patency of no-touch vein graft compared to conventional vein grafts in over 1500 consecutive patients.
作者信息
Ferrari Gabriele, Loayza Richard, Azari Ava, Geijer Håkan, Cao Yang, Carlsson Roland, Bojö Leif, Samano Ninos, Souza Domingos
机构信息
University Health Care Research Centre, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Cardiology and Cardiothoracic Surgery, Blekinge Hospital, Karlskrona, 37181, Sweden.
出版信息
J Cardiothorac Surg. 2024 Oct 1;19(1):570. doi: 10.1186/s13019-024-03057-3.
OBJECTIVES
To evaluate the long-term angiographic patency of saphenous vein grafts (SVG) harvested using the no-touch technique compared to the conventional technique.
METHODS
This was a single-center, retrospective, cohort study. The inclusion criteria were individuals who underwent a CABG (coronary artery bypass grafting) between January 1995 and July 2020, and who successively needed a clinically-driven angiography. The primary endpoint was long-term patency. The secondary endpoints were differences in patency based on sub-group analysis (single vs. sequential graft, divided by target vessel).
RESULTS
The study included 1520 individuals (618 no-touch, 825 conventional and 77 arterial grafts). The mean clinical follow-up time was 8.4 years ± 5.5 years. The patency per patient was 70.7% in the no-touch grafts vs. 46.7% in the conventional grafts (p < 0.001, OR = 2.8). The graft patency was 75.9% in the no-touch grafts vs. 62.8% in the conventional grafts (p < 0.001, OR = 1.8).
CONCLUSIONS
The no-touch vein grafts were associated with statistically significantly higher patency at long-term compared to the conventional grafts.
CLINICAL TRIAL REGISTRATION
NCT04656366, 7 December 2020.
目的
评估与传统技术相比，采用非接触技术获取的大隐静脉移植物（SVG）的长期血管造影通畅率。
方法
这是一项单中心、回顾性队列研究。纳入标准为1995年1月至2020年7月期间接受冠状动脉旁路移植术（CABG）且随后需要进行临床驱动血管造影的个体。主要终点是长期通畅率。次要终点是基于亚组分析（单支与序贯移植物，按靶血管划分）的通畅率差异。
结果
该研究纳入了1520名个体（618例非接触技术、825例传统技术和77例动脉移植物）。平均临床随访时间为8.4年±5.5年。非接触移植物的患者通畅率为70.7%，而传统移植物为46.7%（p<0.001，OR=2.8）。非接触移植物的移植物通畅率为75.9%，传统移植物为62.8%（p<0.001，OR=1.8）。
结论
与传统移植物相比，非接触静脉移植物在长期随访中具有统计学上显著更高的通畅率。
临床试验注册
NCT04656366，2020年12月7日。
Zotero 插件