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澳大利亚 2005-2019 年 2 型糖尿病发病率变化:一项基于人群的研究,总体及按社会人口学特征分析。

Changes in the incidence of type 2 diabetes in Australia, 2005-2019, overall and by socio-demographic characteristics: a population-based study.

机构信息

Baker Heart and Diabetes Institute, Melbourne, VIC.

Monash University, Melbourne, VIC.

出版信息

Med J Aust. 2024 Nov 4;221(9):473-479. doi: 10.5694/mja2.52461. Epub 2024 Oct 1.

Abstract

OBJECTIVES

To estimate changes in the incidence of clinically diagnosed type 2 diabetes in Australia, overall and by age, sex, socio-economic disadvantage, geographic remoteness, and country of birth.

STUDY DESIGN

Population-based study; analysis of National Diabetes Services Scheme (NDSS) data (age-period-cohort models).

SETTING, PARTICIPANTS: Data were extracted for incident cases of type 2 diabetes, 1 January 2005 to 31 December 2019, in residents of the Australian Capital Territory, New South Wales, Queensland, and Victoria aged 20 years or older registered with the NDSS. The numbers of people at risk were obtained from the Australian Bureau of Statistics.

MAIN OUTCOME MEASURES

Changes in the incidence of type 2 diabetes, 2005-2019, by age, postcode-level socio-economic disadvantage (Index of Relative Socioeconomic Disadvantage) and remoteness (major city, inner regional, outer regional/remote/very remote), and country of birth, stratified by sex.

RESULTS

During 2005-2019, 741 535 people aged 20 years or older with incident type 2 diabetes were registered with the NDSS; 421 190 were men (56.8%). Overall, the incidence of type 2 diabetes increased with age (until about age 70 years) and socio-economic disadvantage for both sexes; it was higher in inner regional areas than in major cities or outer regional/remote/very remote areas during 2005-2015, but highest among people in major cities after 2015. The age-standardised incidence of type 2 diabetes increased during 2005-2010, both among men (annual percentage change [APC], 4.4%; 95% confidence interval [CI], 3.6-5.2%) and women (APC, 2.9%; 95% CI, 2.2-3.7%); it declined during 2010-2019 among both men (APC, -5.2%; 95% CI, -5.4% to -4.9%) and women (APC, -6.5%; 95% CI, -6.8% to -6.2%). In general, similar patterns (but of differing magnitude) applied to all age, sex, socio-economic disadvantage, and remoteness groups. However, the incidence of type 2 diabetes increased during 2011-2019 among people born in Asia, North Africa and the Middle East, and the Pacific Islands.

CONCLUSIONS

The incidence of type 2 diabetes in Australian adults declined during 2010-2019 across all age, sex, socio-economic disadvantage, and remoteness groups, but increased among people from Asia, North Africa and the Middle East, and the Pacific Islands.

摘要

目的

估计澳大利亚临床诊断 2 型糖尿病发病率的变化,包括按年龄、性别、社会经济劣势、地理位置偏远程度和出生地进行的分类。

研究设计

基于人群的研究;国家糖尿病服务计划(NDSS)数据分析(年龄-时期-队列模型)。

地点、参与者:提取了 2005 年 1 月 1 日至 2019 年 12 月 31 日期间,在澳大利亚首都领地、新南威尔士州、昆士兰州和维多利亚州登记的 20 岁或以上、参与 NDSS 的 2 型糖尿病患者的发病情况。风险人群数量取自澳大利亚统计局。

主要观察指标

2005-2019 年,按年龄、邮政编码社会经济劣势(相对社会经济劣势指数)和偏远程度(主要城市、内城区、外城区/偏远/非常偏远)、以及性别分层的 2 型糖尿病发病率变化。

结果

2005-2019 年期间,NDSS 登记了 741535 名 20 岁或以上的 2 型糖尿病新发病例;其中 421190 例为男性(56.8%)。总体而言,2 型糖尿病的发病率随年龄增长(直至约 70 岁)和性别相关的社会经济劣势而增加;在 2005-2015 年期间,内城区发病率高于主要城市或外城区/偏远/非常偏远地区,但在 2015 年以后,主要城市居民的发病率最高。2005-2010 年间,男性(APC,4.4%;95%置信区间[CI],3.6-5.2%)和女性(APC,2.9%;95% CI,2.2-3.7%)的 2 型糖尿病年龄标准化发病率均呈上升趋势;在 2010-2019 年间,男性(APC,-5.2%;95% CI,-5.4%至-4.9%)和女性(APC,-6.5%;95% CI,-6.8%至-6.2%)的发病率均呈下降趋势。一般而言,所有年龄、性别、社会经济劣势和偏远程度组均呈现类似模式(但程度不同)。然而,在 2011-2019 年间,来自亚洲、北非和中东以及太平洋岛屿的人群中 2 型糖尿病的发病率有所增加。

结论

2010-2019 年间,澳大利亚成年人的 2 型糖尿病发病率在所有年龄、性别、社会经济劣势和偏远程度组中均呈下降趋势,但来自亚洲、北非和中东以及太平洋岛屿的人群中发病率有所上升。

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