68Ga-DOTATATE PET/CT 显示侵犯下腔静脉和右心房的肾细胞癌伴瘤栓

Renal Cell Carcinoma With Tumor Thrombus Extending Into the Inferior Vena Cava and the Right Atrium Demonstrated by 68 Ga-DOTATATE PET/CT.

机构信息

From the Department of Nuclear Medicine, University of Health Sciences, Kartal Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey.

Department of Nuclear Medicine, Marmara University Pendik Training and Research Hospital, Istanbul, Turkey.

出版信息

Clin Nucl Med. 2024 Nov 1;49(11):e630-e631. doi: 10.1097/RLU.0000000000005487. Epub 2024 Oct 1.

DOI:10.1097/RLU.0000000000005487

PMID:39354686

Abstract

Approximately 10% of all renal cell carcinoma (RCC) patients develop a venous tumor thrombus, a major negative prognostic factor. Surgical excision is commonly required for RCC patients with tumor thrombus. Accurate preoperative diagnosis and assessment of tumor thrombus level is vital because the level of thrombus may influence treatment decisions. MRI, contrast-enhanced CT, 18 F-FDG PET/CT, and 68 Ga-PSMA PET/CT have been used to diagnose and evaluate the extent of tumor thrombus in RCC. However, no case of RCC with inferior vena cava tumor thrombus showing 68 Ga-DOTATATE uptake has been reported yet. Herein, we report a case of metastatic RCC with tumor thrombus in the inferior vena cava on 68 Ga-DOTATATE PET/CT.

摘要

约 10%的肾细胞癌 (RCC) 患者会发生静脉肿瘤血栓，这是一个主要的预后不良因素。对于患有肿瘤血栓的 RCC 患者，通常需要进行手术切除。准确的术前诊断和评估肿瘤血栓水平至关重要，因为血栓水平可能会影响治疗决策。MRI、增强 CT、18 F-FDG PET/CT 和 68 Ga-PSMA PET/CT 已被用于诊断和评估 RCC 中肿瘤血栓的程度。然而，目前尚未有报告显示 RCC 合并下腔静脉肿瘤血栓摄取 68 Ga-DOTATATE 的病例。在此，我们报告一例转移性 RCC 合并下腔静脉肿瘤血栓患者的 68 Ga-DOTATATE PET/CT 检查结果。