Ali Yahia H, Mohieddeen Tenzeil A G, Abdellatif Muaz M, Ahmed Baraa Mohammed, Saeed Intisar K, Attaalfadeel Husham M, Ali Amani A
Department of Biology, College of Science and Arts, Rafha, Northern Border University, Arar, Saudi Arabia; and Virology Department, Central Veterinary Research Laboratory, Khartoum.
Onderstepoort J Vet Res. 2024 Sep 26;91(1):e1-e10. doi: 10.4102/ojvr.v91i1.2181.
Rabies is endemic in Sudan with continuing outbreaks occurring annually, the most common animals affected are dogs, followed by goats and equids. This work focused on equid rabies, to elucidate the current situation of the disease through analysis of reports of equid rabies outbreaks in Sudan during 2010-2022 supported by laboratory confirmation of the disease. During the study period, 66 animals were affected during 35 equid rabies outbreaks. The highest incidences were found in Al Gezira (30.3%), followed by Darfur (24.2%) and Kordofan (15.2%). The highest incidence rate was observed during 2018 (33.3%), followed by 2015 (16.7%). Within seasons, the highest incidence rate was reported during October - December (33.3%), followed by July - September (30.3%). Chi-square analysis revealed a significant correlation between rabid animals and year, season, and state. Wald statistics demonstrated that year and season had a significant association with the disease. Virus antigen was identified (72.2%) in brain tissues using the fluorescent antibody test. Viral nucleic acid was amplified (n = 6) with a reverse transcriptase polymerase chain reaction assay.Contribution: As equids are kept in close contact with humans and other animals in the country, according to the present investigation, equid rabies in Sudan is a potential public health concern, emphasising the importance of implementing effective control measures.
狂犬病在苏丹呈地方流行状态,每年都有持续的疫情爆发,受影响最常见的动物是狗,其次是山羊和马科动物。这项工作聚焦于马科动物狂犬病,通过分析2010年至2022年苏丹马科动物狂犬病疫情报告,并辅以该疾病的实验室确诊,来阐明该疾病的现状。在研究期间,35起马科动物狂犬病疫情中有66只动物受到影响。发病率最高的是杰济拉州(30.3%),其次是达尔富尔州(24.2%)和科尔多凡州(15.2%)。发病率最高的年份是2018年(33.3%),其次是2015年(16.7%)。在各个季节中,10月至12月的发病率最高(33.3%),其次是7月至9月(30.3%)。卡方分析显示,患狂犬病的动物与年份、季节和州之间存在显著相关性。Wald统计表明,年份和季节与该疾病有显著关联。使用荧光抗体试验在脑组织中鉴定出病毒抗原(72.2%)。通过逆转录聚合酶链反应测定法扩增了病毒核酸(n = 6)。贡献:由于在该国马科动物与人类和其他动物密切接触,根据目前的调查,苏丹的马科动物狂犬病是一个潜在的公共卫生问题,强调了实施有效控制措施的重要性。