Onuma Ryo, Hoshi Fumihiko, Yamasaki Hiroshi R, Tozawa Ryosuke, Sakai Tomoko, Jinno Tetsuya
Faculty of Health Science, Mejiro University: 320 Ukiya, Saitama-shi, Saitama 339-8501, Japan.
Department of Rehabilitation Medicine, Tokyo Medical and Dental University Graduate School, Japan.
J Phys Ther Sci. 2024 Oct;36(10):667-671. doi: 10.1589/jpts.36.667. Epub 2024 Oct 1.
[Purpose] One-leg standing motion was measured in patients with Parkinson's disease (PD) to evaluate the association between freezing of gait (FOG) and anticipatory postural adjustments (APA). [Participants and Methods] The participants included10 healthy older individuals, seven patients with PD without FOG (PD-FOG group), and seven patients with PD and FOG (PD+FOG group). An accelerometer that was built into a smartphone was attached to the lower back of each participant, and acceleration in the mediolateral direction was measured during one-leg standing. For the mediolateral component of acceleration, the time to the maximum value in the stance direction (peak latency, PL) and the amount of displacement of the maximum value (peak magnitude, PM) were analyzed as APA features. A one-way analysis of variance (ANOVA) was used to compare PL and PM among the three groups. In addition, the APA ratio (APAr), which is the ratio of PL to PM, was compared between study cohorts. [Results] Delayed PL and decreased PM were observed in the PD+FOG group, compared with the older and PD-FOG groups. In addition, APAr levels were significantly lower in the PD+FOG group. [Conclusion] Patients with PD with FOG had greater APA impairment than those with PD without FOG.
[目的] 对帕金森病（PD）患者进行单腿站立运动测量，以评估冻结步态（FOG）与预期姿势调整（APA）之间的关联。[参与者与方法] 参与者包括10名健康老年人、7名无FOG的PD患者（PD-FOG组）和7名有FOG的PD患者（PD+FOG组）。将内置在智能手机中的加速度计附着于每位参与者的下背部，并在单腿站立期间测量中外侧方向的加速度。对于加速度的中外侧分量，将站立方向上达到最大值的时间（峰值潜伏期，PL）和最大值的位移量（峰值幅度，PM）作为APA特征进行分析。采用单因素方差分析（ANOVA）比较三组之间的PL和PM。此外，还比较了研究队列之间的APA比率（APAr），即PL与PM的比率。[结果] 与老年组和PD-FOG组相比，PD+FOG组观察到PL延迟和PM降低。此外，PD+FOG组的APAr水平显著较低。[结论] 有FOG的PD患者比无FOG的PD患者有更严重的APA损害。
