Cumitini Luca, Giubertoni Ailia, Patti Giuseppe
Department of Translational Medicine, University of Eastern Piedmont, 28100 Novara, Italy.
Division of Cardiology, Maggiore della Carità Hospital, 28100 Novara, Italy.
Rev Cardiovasc Med. 2024 Sep 20;25(9):336. doi: 10.31083/j.rcm2509336. eCollection 2024 Sep.
Transcatheter valve procedures have become a cornerstone in the management of patients with valvular heart disease and high surgical risk, especially for aortic stenosis and mitral and tricuspid regurgitation. Cardiopulmonary exercise testing (CPET) is generally considered the gold standard for objectively quantifying functional capacity, providing a comprehensive evaluation of the human body's performance, particularly in patients with heart failure (HF). Its accurate assessment is valuable for exploring the pathogenetic mechanisms implicated in HF-related functional impairment. It is also useful for objectively staging the clinical severity and the prognosis of the disease. The improvement in functional capacity after transcatheter valve procedures may be clinically relevant and may provide prognostic information, even in this setting. However, it remains to be fully determined as data on the topic are limited. This review aims to summarize the available evidence on the usefulness of CPET to assess functional improvement in patients undergoing transcatheter valve procedures.
经导管瓣膜手术已成为治疗瓣膜性心脏病且手术风险高的患者的基石，尤其是对于主动脉瓣狭窄以及二尖瓣和三尖瓣反流患者。心肺运动试验（CPET）通常被认为是客观量化功能能力的金标准，可对人体机能进行全面评估，特别是对于心力衰竭（HF）患者。其准确评估对于探究与HF相关功能障碍的发病机制具有重要价值。它对于客观判断疾病的临床严重程度和预后也很有用。即使在此情况下，经导管瓣膜手术后功能能力的改善在临床上可能具有相关性，并且可能提供预后信息。然而，由于该主题的数据有限，这一点仍有待充分确定。本综述旨在总结关于CPET在评估接受经导管瓣膜手术患者功能改善方面有用性的现有证据。
