Khodeir Joe, Ohanian Paul, Megarbane Hala Abi Rached
Department of Dermatology at Saint Georges Hospital University Medical Center, Faculty of Medicine and Medical Sciences University of Balamand Beirut Lebanon.
Department of Family Medicine at Saint Georges Hospital University Medical Center, Faculty of Medicine and Medical Sciences University of Balamand Beirut Lebanon.
Clin Case Rep. 2024 Sep 30;12(10):e9392. doi: 10.1002/ccr3.9392. eCollection 2024 Oct.
Chromoblastomycosis, though rare in non-endemic regions like Lebanon, should be considered in patients presenting with chronic, verrucous skin lesions unresponsive to conventional therapies. Multimodal treatment combining oral antifungals, cryotherapy, and adjunctive topical 5-Fluorouracil demonstrates efficacy in managing refractory cases. Follow-up visits three and 6 months after treatment cessation showed sustained lesion clearance and no recurrence.
着色芽生菌病在黎巴嫩等非流行地区虽罕见,但对于出现慢性、疣状皮肤病变且对传统疗法无反应的患者应予以考虑。口服抗真菌药、冷冻疗法及辅助外用5-氟尿嘧啶的多模式治疗在处理难治性病例方面显示出疗效。治疗停止后3个月和6个月的随访显示病变持续清除且无复发。