评估一种碘代异恶唑鎓（III）盐的卤键强度。
Evaluating the halogen bonding strength of a iodoloisoxazolium(III) salt.
作者信息
Reinhard Dominik L, Schmidt Anna, Sons Marc, Wolf Julian, Engelage Elric, Huber Stefan M
机构信息
Fakultät für Chemie und Biochemie, Ruhr-Universität Bochum, Universitätsstraße 150, 44801 Bochum, Germany.
出版信息
Beilstein J Org Chem. 2024 Sep 23;20:2401-2407. doi: 10.3762/bjoc.20.204. eCollection 2024.
Diaryliodonium(III) salts have been established as powerful halogen-bond donors in recent years. Herein, a new structural motif for this compound class was developed: iodoloisoxazolium salts, bearing a cyclic five-membered iodolium core fused with an isoxazole ring. A derivative of this class was synthesized and investigated in the solid state by X-ray crystallography. Finally, the potential as halogen-bonding activator was benchmarked in solution in the gold-catalyzed cyclization of a propargyl amide.
近年来，二芳基碘鎓（III）盐已被确立为强大的卤素键供体。在此，开发了这类化合物的一种新结构 motif：碘代异恶唑鎓盐，其具有与异恶唑环稠合的环状五元碘鎓核心。合成了该类的一种衍生物，并通过X射线晶体学对其固态进行了研究。最后，在炔丙基酰胺的金催化环化反应中，在溶液中对其作为卤素键活化剂的潜力进行了基准测试。
Zotero 插件