Fallah Soheila, Parnain Zahra, Taghavi-Azar-Sharabiani Parvaneh, Cheraghifard Moslem, Vasaghi-Gharamaleki Behnoosh, Roohi-Azizi Mahtab, Hashemi Mansoureh, Yousefi Mahin, Joghataei Mohammad-Taghi, Taghizadeh Ghorban
Department of Neurosciences, Faculty of Advanced Technologies in Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Department of Occupational Therapy, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Top Stroke Rehabil. 2025 May;32(4):405-418. doi: 10.1080/10749357.2024.2408997. Epub 2024 Oct 2.
This research sought to ascertain the Minimal Clinically Important Difference (MCID) and Robust Clinically Important Difference (RCID) of the Multidimensional Fatigue Symptom Inventory-Short Form (MFSI-SF) and Chalder Fatigue Questionnaire-11 (CFQ-11) as two important concepts for the clinical interpretation of the results in chronic post-stroke population.
A total of 128 subjects with chronic post-stroke completed the MFSI-SF and CFQ-11 before and after six weeks of intervention. The MCIDs were derived using both anchor- and distribution-based methods; however, only anchor-based methods were used to estimate RCIDs.
Anchor-based MCIDs for MFSI-SF and CFQ-11 were in the range of -5 to -6.28 and -2 to -4.56, respectively. Distribution-based MCIDs in MFSI-SF and CFQ-11 were calculated in the range of -4.17 to -24.05 and -1.72 to -7.68, respectively. RCID ranges of -10 to -15 were obtained for the MFSI-SF and -6 to -7.33 for the CFQ-11.
These findings may have implications for clinical experts in the clinical interpretation of fatigue changes observed in MFSI-SF and CFQ-11 in individuals with chronic stroke.
本研究旨在确定多维疲劳症状简表（MFSI-SF）和查尔德疲劳问卷11项版（CFQ-11）的最小临床重要差异（MCID）和稳健临床重要差异（RCID），这是慢性卒中患者群体临床结果解读中的两个重要概念。
共有128名慢性卒中患者在干预六周前后完成了MFSI-SF和CFQ-11。MCID采用基于锚定和基于分布的方法得出；然而，仅使用基于锚定的方法来估计RCID。
MFSI-SF和CFQ-11基于锚定的MCID分别在-5至-6.28和-2至-4.56范围内。MFSI-SF和CFQ-11基于分布的MCID分别计算在-4.17至-24.05和-1.72至-7.68范围内。MFSI-SF的RCID范围为-10至-15，CFQ-11的RCID范围为-6至-7.33。
这些发现可能对临床专家解读慢性卒中患者MFSI-SF和CFQ-11中观察到的疲劳变化具有临床意义。
