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Enhancing Asthma Pharmacogenetics Through Subtype-Specific Associations.

作者信息

Piparia Shraddha, Hecker Julian, Srivastava Upasna, Sharma Rinku, Khare Manaswitha, Kho Alvin, Weiss Scott T, McGeachie Michael, Tantisira Kelan

机构信息

Division of Pediatric Respiratory Medicine, University of California at San Diego, San Diego, California, USA.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Clin Exp Allergy. 2025 Feb;55(2):193-195. doi: 10.1111/cea.14573. Epub 2024 Oct 2.

DOI:10.1111/cea.14573
PMID:39357540
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11794022/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dee3/11794022/797f8dc3607c/nihms-2025101-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dee3/11794022/797f8dc3607c/nihms-2025101-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dee3/11794022/797f8dc3607c/nihms-2025101-f0001.jpg

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本文引用的文献

1
Are We Meeting the Promise of Endotypes and Precision Medicine in Asthma?我们是否满足了哮喘的表型和精准医学的承诺？
Physiol Rev. 2020 Jul 1;100(3):983-1017. doi: 10.1152/physrev.00023.2019. Epub 2020 Jan 9.
2
Predicting inhaled corticosteroid response in asthma with two associated SNPs.用两个相关的 SNP 预测哮喘患者吸入皮质激素的反应。
Pharmacogenomics J. 2013 Aug;13(4):306-11. doi: 10.1038/tpj.2012.15. Epub 2012 May 29.
3
Genome-wide association identifies the T gene as a novel asthma pharmacogenetic locus.全基因组关联分析鉴定 T 基因是一个新的哮喘药物遗传学位点。
Am J Respir Crit Care Med. 2012 Jun 15;185(12):1286-91. doi: 10.1164/rccm.201111-2061OC. Epub 2012 Apr 26.
4
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.GLCCI1 基因与哮喘患者糖皮质激素治疗反应的全基因组关联研究。
N Engl J Med. 2011 Sep 29;365(13):1173-83. doi: 10.1056/NEJMoa0911353. Epub 2011 Sep 26.
5
PLINK: a tool set for whole-genome association and population-based linkage analyses.PLINK：一个用于全基因组关联分析和基于群体的连锁分析的工具集。
Am J Hum Genet. 2007 Sep;81(3):559-75. doi: 10.1086/519795. Epub 2007 Jul 25.
6
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids.皮质类固醇药物遗传学：CRHR1基因序列变异与吸入皮质类固醇治疗的哮喘患者肺功能改善的关联
Hum Mol Genet. 2004 Jul 1;13(13):1353-9. doi: 10.1093/hmg/ddh149. Epub 2004 May 5.
7
Long-term effects of budesonide or nedocromil in children with asthma.布地奈德或奈多罗米对哮喘儿童的长期影响。
N Engl J Med. 2000 Oct 12;343(15):1054-63. doi: 10.1056/NEJM200010123431501.
8
The Childhood Asthma Management Program (CAMP): design, rationale, and methods. Childhood Asthma Management Program Research Group.儿童哮喘管理项目（CAMP）：设计、基本原理及方法。儿童哮喘管理项目研究组
Control Clin Trials. 1999 Feb;20(1):91-120.
9
Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach.比较两条或多条相关的受试者工作特征曲线下的面积：一种非参数方法。
Biometrics. 1988 Sep;44(3):837-45.