负载基质：用于帕金森病干细胞脑修复的富含神经营养因子的水凝胶 - Suppr

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超能文献

The loaded matrix: neurotrophin-enriched hydrogels for stem cell brain repair in Parkinson's disease.

作者信息

Comini Giulia, Dowd Eilis

机构信息

Pharmacology & Therapeutics, University of Galway, Galway, Ireland.

出版信息

Neural Regen Res. 2025 Aug 1;20(8):2315-2316. doi: 10.4103/NRR.NRR-D-24-00586. Epub 2024 Jul 29.

DOI:10.4103/NRR.NRR-D-24-00586

PMID:39359086

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11759036/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67be/11759036/e538ac579f3b/NRR-20-2315-g001.jpg

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本文引用的文献

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Restorative cell and gene therapies for Parkinson's disease.帕金森病的修复细胞和基因治疗。

Handb Clin Neurol. 2023;193:211-226. doi: 10.1016/B978-0-323-85555-6.00012-6.

Hydrogels for brain repair: application to Parkinson's disease.水凝胶在脑修复中的应用：帕金森病。

Expert Opin Drug Deliv. 2022 Nov;19(11):1521-1537. doi: 10.1080/17425247.2022.2136161. Epub 2022 Nov 1.

The potential of biomaterials for central nervous system cellular repair.生物材料在中枢神经系统细胞修复中的潜力。

Neurochem Int. 2021 Mar;144:104971. doi: 10.1016/j.neuint.2021.104971. Epub 2021 Jan 28.

Harnessing stem cells and biomaterials to promote neural repair.利用干细胞和生物材料促进神经修复。

Br J Pharmacol. 2019 Feb;176(3):355-368. doi: 10.1111/bph.14545. Epub 2018 Dec 21.

Encapsulation of young donor age dopaminergic grafts in a GDNF-loaded collagen hydrogel further increases their survival, reinnervation, and functional efficacy after intrastriatal transplantation in hemi-Parkinsonian rats.将年轻供体来源的多巴胺能移植物包裹在负载 GDNF 的胶原水凝胶中，可进一步增加其在半帕金森病大鼠纹状体内移植后的存活、再神经支配和功能效果。

Eur J Neurosci. 2019 Feb;49(4):487-496. doi: 10.1111/ejn.14090. Epub 2018 Aug 12.

Brain repair for Parkinson's disease: is the answer in the matrix?帕金森病的脑修复：答案在基质中吗？

Neural Regen Res. 2018 Jul;13(7):1187-1188. doi: 10.4103/1673-5374.235027.

Primary tissue for cellular brain repair in Parkinson's disease: Promise, problems and the potential of biomaterials.用于帕金森病脑细胞修复的主要组织：生物材料的前景、问题和潜力。

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