新型冠状病毒肺炎相关肺空洞性病变：病例系列
COVID-19 associated lung cavitary lesions: A case series.
作者信息
Bozorgmehr Rama, Esmaili Tarki Farzad, Yazdi Esmat, Shahrokhi Nejad Shahrzad
机构信息
Clinical Research Development Unit, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahid Beheshti University of Medical Sciences, Tehran, Iran.
出版信息
Caspian J Intern Med. 2024 Sep 7;15(4):713-728. doi: 10.22088/cjim.15.4.713. eCollection 2024 Fall.
BACKGROUND
Our study discusses the probable etiologies and characteristics of pulmonary cavities in post-COVID-19 patients. A pulmonary cavity is a late complication of the disease, yet it has led to multiple referrals to our tertiary hospital in Tehran, Iran.
METHODS
We conducted a retrospective case-series study on 20 patients who were admitted to our center between April 2020 and September 2021. They were all diagnosed with COVID-19 and concomitantly developed pulmonary cavities. We assessed their electronic medical records in 2021 and compared their characteristics with other studies based on the available literature.
RESULT
Of the 20 patients with cavities, 12 (60%) had been diagnosed with prior COVID-19, and 9 (45%) had type 2 diabetes mellitus. 9 patients (45%) had bacterial superinfections while 4 (44%) had fungal infections. All patients received corticosteroids, but only 4 (20%) were additionally administered Tocilizumab.
CONCLUSION
COVID-19 patients can develop pulmonary cavities during recovery; however, this infrequent radiologic finding depends on specific risk factors.
背景
我们的研究探讨了新冠病毒病康复期患者肺空洞的可能病因及特征。肺空洞是该疾病的一种晚期并发症，但它已导致多例患者转诊至伊朗德黑兰的我们这家三级医院。
方法
我们对2020年4月至2021年9月期间入住我们中心的20例患者进行了一项回顾性病例系列研究。他们均被诊断为新冠病毒病，且同时并发了肺空洞。我们于2021年评估了他们的电子病历，并根据现有文献将其特征与其他研究进行了比较。
结果
在20例有空洞的患者中，12例（60%）先前被诊断为新冠病毒病，9例（45%）患有2型糖尿病。9例患者（45%）发生了细菌重叠感染，4例（44%）发生了真菌感染。所有患者均接受了皮质类固醇治疗，但只有4例（20%）额外使用了托珠单抗。
结论
新冠病毒病患者在康复过程中可能会出现肺空洞；然而，这种不常见的影像学表现取决于特定的危险因素。
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