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利用骨转移癌多学科会诊对孕期乳腺癌相关多发骨转移进行多学科治疗:一例报告

Multidisciplinary Treatment for Breast Cancer-related Multiple Bone Metastases during Pregnancy Using Bone Metastasis Cancer Boards: A Case Report.

作者信息

Kashima Ryoga, Yoshikawa Ryo, Saho Wataru, Nakamura Ken, Tsuda Yuzo, Harada Risa, Tatebayashi Daisuke, Sawada Ryoko, Kunihisa Tomonari, Sakai Yoshitada

机构信息

Department of Physical Medicine and Rehabilitation, Kobe University Hospital, Kobe, Japan.

Division of Rehabilitation Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

出版信息

Prog Rehabil Med. 2024 Oct 2;9:20240032. doi: 10.2490/prm.20240032. eCollection 2024.

Abstract

BACKGROUND

In patients vulnerable to skeletal-related events (SREs), a multidisciplinary approach is required to manage risk and determine the best treatment plan. We have used Bone Metastasis Cancer Boards (BMCBs) to deliver multidisciplinary treatments in our hospital since 2013. Here, we report a case in which we used BMCBs to coordinate multidisciplinary treatment for a pregnant patient with breast cancer and multiple bone metastases.

CASE

A 41-year-old pregnant woman was admitted to our hospital because low back pain compromised her ability to stand. She was diagnosed with breast cancer-associated multiple bone metastases. Our unit was consulted for rehabilitation therapy, for which we formed a BMCB. The treatment was integrated and performed according to the recommendations of the BMCB. The patient underwent a cesarean section to initiate primary tumor treatment. After evaluating the risk of SREs, we provided her with rehabilitation therapy. Wearing a plastic molded thoracolumbosacral orthosis, she was able to walk with a pick-up walker. The patient continued outpatient chemotherapy and cared for her infant without experiencing any significant adverse events.

DISCUSSION

In this case, we formed our BMCB to determine the treatment plan, which we used to support the patient's needs during childbirth and successfully improved her activities of daily living. BMCBs can contribute to preventing SREs and provide effective rehabilitation therapy for patients with bone metastases. We aspire to continually gather experience through our BMCBs and contribute to the establishment of evidence regarding the effectiveness of rehabilitation therapy for patients with bone metastases.

摘要

背景

在易发生骨相关事件(SREs)的患者中,需要采用多学科方法来管理风险并确定最佳治疗方案。自2013年以来,我们医院一直使用骨转移癌诊疗小组(BMCBs)来提供多学科治疗。在此,我们报告一例使用BMCBs为一名患有乳腺癌和多处骨转移的孕妇协调多学科治疗的病例。

病例

一名41岁孕妇因腰痛导致无法站立而入院。她被诊断为乳腺癌相关的多处骨转移。我们科室被咨询进行康复治疗,为此我们组建了一个BMCB。治疗是综合进行的,并根据BMCB的建议实施。患者接受了剖宫产以开始原发性肿瘤治疗。在评估SREs风险后,我们为她提供了康复治疗。她佩戴了塑形胸腰骶矫形器,能够借助助行器行走。患者继续接受门诊化疗并照顾婴儿,未出现任何重大不良事件。

讨论

在本病例中,我们组建BMCB以确定治疗方案,该方案用于在分娩期间支持患者需求,并成功改善了她的日常生活活动能力。BMCBs有助于预防SREs,并为骨转移患者提供有效的康复治疗。我们希望通过我们的BMCBs不断积累经验,并为确立骨转移患者康复治疗有效性的证据做出贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443e/11443026/82329d243f75/prm-9-20240032-g001.jpg

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