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评估胎儿多普勒超声在高危产科中的作用:一项综合研究的证据

Assessing the Role of Fetal Doppler in High-Risk Obstetrics: Evidence From a Comprehensive Study.

作者信息

Kolate Dipak, Suryarao Prashant, Bhattacharjee Nikita, Sansare Swapnali

机构信息

Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.

出版信息

Cureus. 2024 Sep 1;16(9):e68383. doi: 10.7759/cureus.68383. eCollection 2024 Sep.

Abstract

Background Colour Doppler ultrasound is pivotal in modern obstetrics for evaluating maternal and fetal health, especially in high-risk pregnancies. It enhances fetal oxygenation and nutrient delivery assessment, aiding in the early detection of adverse outcomes. However, its effectiveness is influenced by operator skill and the potential for interpretative variability. Aim This study aims to assess the utility of Doppler ultrasound in evaluating fetal status in high-risk pregnancies at Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, India. Materials and methods A hospital-based observational study was conducted from September 2022 to July 2024, including 145 high-risk pregnant women, of whom 120 delivered at the institute. The study included thorough maternal and fetal assessments, with regular Doppler studies starting at 28 weeks of gestation. The frequency of these studies was adjusted according to the changes and severity observed in the indices. Detailed documentation of both maternal and neonatal outcomes was meticulously maintained. Statistical analyses were performed using MS Excel (Microsoft® Corp., Redmond, WA, USA) and RStudio, Version 2023.08.0-daily+170 (RStudio, Inc., Boston, MA, USA), with a significance threshold of p < 0.05. Results The majority of participants were aged 21-30 years, with multigravida constituting 63.33%. Pregnancy-induced hypertension (PIH) and preeclampsia were the most common high-risk factors (28.33%). Abnormal umbilical artery (UA) flow patterns were observed in 58.33% of cases. Abnormal UA and middle cerebral artery (MCA) Doppler indices correlated significantly with adverse outcomes. Most deliveries were via caesarean section (82.5%), and 63.33% of neonates required Neonatal Intensive Care Unit (NICU) admission. Neonates with abnormal antenatal Doppler studies had significantly lower APGAR (appearance, pulse, grimace, activity, and respiration) scores and higher NICU admission rates. Discussion The study highlights the critical role of Doppler ultrasound in managing high-risk pregnancies, providing essential data for early interventions. Consistent with other studies, abnormal Doppler patterns were significantly associated with adverse neonatal outcomes, necessitating timely caesarean deliveries. Conclusion Fetal Doppler ultrasonography is essential for managing high-risk pregnancies, enabling timely therapeutic interventions and improving perinatal outcomes. Despite its limitations, Doppler technology remains invaluable in identifying at-risk foetuses and guiding clinical decisions for optimal pregnancy management.

摘要

背景

彩色多普勒超声在现代产科中对于评估母婴健康至关重要,尤其是在高危妊娠中。它增强了对胎儿氧合和营养供应的评估,有助于早期发现不良结局。然而,其有效性受到操作者技能和解释变异性的影响。

目的

本研究旨在评估印度浦那迪帕克蒂尔医学院、医院及研究中心使用多普勒超声评估高危妊娠胎儿状况的效用。

材料与方法

2022年9月至2024年7月进行了一项基于医院的观察性研究,纳入145名高危孕妇,其中120名在该机构分娩。该研究包括对母亲和胎儿的全面评估,从妊娠28周开始定期进行多普勒检查。这些检查的频率根据观察到的指标变化和严重程度进行调整。精心记录母亲和新生儿的详细结局。使用MS Excel(美国华盛顿州雷德蒙德微软公司)和RStudio 2023.08.0 - daily + 170版本(美国马萨诸塞州波士顿RStudio公司)进行统计分析,显著性阈值为p < 0.05。

结果

大多数参与者年龄在21 - 30岁之间,经产妇占63.33%。妊娠高血压疾病(PIH)和子痫前期是最常见的高危因素(28.33%)。58.33%的病例观察到脐动脉(UA)血流模式异常。异常的UA和大脑中动脉(MCA)多普勒指标与不良结局显著相关。大多数分娩通过剖宫产进行(82.5%),63.33%的新生儿需要入住新生儿重症监护病房(NICU)。产前多普勒检查异常的新生儿阿氏评分(外观、脉搏、 grimace、活动和呼吸)显著较低,入住NICU的比例较高。

讨论

该研究强调了多普勒超声在管理高危妊娠中的关键作用,为早期干预提供了重要数据。与其他研究一致,异常的多普勒模式与不良新生儿结局显著相关,需要及时进行剖宫产。

结论

胎儿多普勒超声检查对于管理高危妊娠至关重要,能够实现及时的治疗干预并改善围产期结局。尽管存在局限性,多普勒技术在识别高危胎儿和指导最佳妊娠管理的临床决策方面仍然非常宝贵。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b64/11445665/22d5200ccdc2/cureus-0016-00000068383-i01.jpg

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