Besagar Sonya, de-la-Torre Alejandra, Thorne Jennifer, Biswas Jyotirmay, Agrawal Rupesh, Suhler Eric B, Kempen John H, Gangaputra Sapna
Vanderbilt Eye Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Neuroscience Research Group (NEUROS), Neurovitae Center for Neuroscience, Institute of Translational Medicine (IMT), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia.
Ocul Immunol Inflamm. 2025 May;33(4):503-511. doi: 10.1080/09273948.2024.2408411. Epub 2024 Oct 3.
Intermediate uveitis is defined as inflammation of the vitreous and pars planitis. Etiology can be infectious, associated with a systemic disease, neoplastic or idiopathic. Pars planitis is the term used for idiopathic intermediate uveitis that presents with snowballs and snowbanks. While relatively rare, intermediate uveitis is present globally and typically affects adult females. Awareness of the presentation and a dilated fundus examination in patients presenting with floaters is essential to the diagnosis. PCR testing has enhanced the ability to diagnose infectious and neoplastic conditions that masquerade as intermediate uveitis. A structured review of systems and focused imaging, and laboratory testing will assist with early diagnosis and initiation of treatment.
中间葡萄膜炎被定义为玻璃体和睫状体平坦部炎。病因可以是感染性的、与全身性疾病相关、肿瘤性的或特发性的。睫状体平坦部炎是用于描述表现为雪球样和雪堤样改变的特发性中间葡萄膜炎的术语。虽然相对罕见,但中间葡萄膜炎在全球范围内都有发生,且通常影响成年女性。对于出现飞蚊症的患者,了解其临床表现并进行散瞳眼底检查对诊断至关重要。聚合酶链反应(PCR)检测提高了诊断伪装成中间葡萄膜炎的感染性和肿瘤性疾病的能力。对系统进行结构化回顾以及针对性的影像学和实验室检查将有助于早期诊断和开始治疗。