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机器人辅助女性人工尿失禁括约肌植入术与男性人工尿失禁括约肌植入术治疗非神经源性压力性尿失禁的比较。

Robotic female artificial urinary sphincter implantation vs. male artificial urinary sphincter implantation for non-neurogenic stress urinary incontinence.

机构信息

Department of Urology, University Hospital of Rennes, Rennes, France.

Department of Urology, Polyclinique Saint Jean, Cagnes-sur-Mer, France.

出版信息

World J Urol. 2024 Oct 3;42(1):557. doi: 10.1007/s00345-024-05238-0.

Abstract

PURPOSE

Previous studies suggested better functional outcomes and longer device survival for female artificial urinary sphincter (AUS) implantation compared to male AUS implantation. We hypothesized that the adoption of robotic approaches for female implantation might have influenced these comparisons. This study aimed to compare the outcomes of robotic female AUS and male AUS implantation for non-neurogenic stress urinary incontinence (SUI).

METHODS

We retrospectively reviewed charts of male patients who had AUS implantation and female patients who underwent robotic AUS implantation for non-neurogenic SUI between 2010 and 2022 at a single center. Prior AUS implantations were exclusion criteria. The primary endpoint was continence status at 3 months, categorized as complete resolution of SUI (0 pad), improved SUI (1pad), or unchanged SUI (>1pad).

RESULTS

After excluding 79 patients, 171 were included: 70 women and 101 men. Operative time was shorter in males (126.9 vs. 165.5 min; p < 0.0001). Postoperative complication rates were similar (17.3% vs. 22.9%; p = 0.38). Continence status at 3 months and last follow-up favored females. The ICIQ-SF decrease at 3 months was greater in females (-7.2 vs. -4.6; p < 0.001). The 5-year estimated explantation-free survival was similar (78.6% vs. 73.7%; p = 0.94) as was the revision-free survival (67.4% vs. 61.7%; p = 0.89). Multivariate analysis showed that female gender was associated with better continence at last follow-up (OR = 4.3; p = 0.03).

CONCLUSION

Robotic female AUS implantation is associated with better functional outcomes than male AUS implantation, with similar morbidity and survival rates.

摘要

目的

先前的研究表明,与男性人工尿道括约肌(AUS)植入相比,女性 AUS 植入的功能结果更好,设备存活率更高。我们假设,采用机器人方法进行女性植入可能会影响这些比较。本研究旨在比较机器人辅助女性 AUS 和男性 AUS 植入治疗非神经源性压力性尿失禁(SUI)的结果。

方法

我们回顾性分析了 2010 年至 2022 年期间在一家单中心接受 AUS 植入的男性患者和接受机器人辅助女性 AUS 植入的非神经源性 SUI 女性患者的病历。排除先前的 AUS 植入史。主要终点是 3 个月时的控尿状态,分为 SUI 完全缓解(0 片)、SUI 改善(1 片)或 SUI 无变化(>1 片)。

结果

排除 79 例患者后,共纳入 171 例患者:70 例女性和 101 例男性。男性手术时间更短(126.9 分钟 vs. 165.5 分钟;p<0.0001)。术后并发症发生率相似(17.3% vs. 22.9%;p=0.38)。3 个月和最后随访时的控尿状态更倾向于女性。女性在 3 个月时的 ICIQ-SF 评分下降更大(-7.2 分 vs. -4.6 分;p<0.001)。5 年估计免取出率相似(78.6% vs. 73.7%;p=0.94),免翻修率也相似(67.4% vs. 61.7%;p=0.89)。多变量分析显示,女性性别与最后随访时的更好控尿相关(OR=4.3;p=0.03)。

结论

机器人辅助女性 AUS 植入与男性 AUS 植入相比,功能结果更好,发病率和存活率相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a49/11449989/3d4a873409b8/345_2024_5238_Fig1_HTML.jpg

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