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Lethal Self-Administration of Atracurium: A Rarely Reported Case with Review of Literature.

作者信息

Galoria Darshan, Shukla Srushti, Datta Arijit, Das Abhishek, Goswami Dhara, Rana Pradip, Tiwari Preeti

机构信息

From the Resident, Forensic Medicine and Toxicology, Pramukhswami Medical College and Shree Krishna Hospital, Karamsad, Gujarat, India.

Associate Professor, Forensic Medicine and Toxicology, Pramukhswami Medical College and Shree Krishna Hospital, Karamsad, Gujarat, India.

出版信息

Am J Forensic Med Pathol. 2025 Mar 1;46(1):79-81. doi: 10.1097/PAF.0000000000000985. Epub 2024 Oct 4.

DOI:10.1097/PAF.0000000000000985
PMID:39361255
Abstract

Atracurium besylate is a nondepolarizing skeletal muscle relaxant first introduced in 1980. It is used during endotracheal intubation. It causes muscle relaxation during surgery or mechanical ventilation. When people consider suicide, they employ drugs found in their surroundings but not usually injectable muscle relaxants, which are not widely available. Studies on their use in suicide are rarely reported worldwide. This was a case of a 34-year-old male nursing staff, working in the general surgery department's operation theater complex, who was found unconscious in bed in his room in the morning with an empty syringe by the bedside. He was declared dead when brought to the emergency department. Forensic autopsy was conducted, and during the external examination, a needle puncture wound was found over the left cubital fossa. No other external other injuries were observed throughout the body. The toxicological analysis report indicated the presence of laudanosine in the vitreous humor, blood, urine, and skin from the puncture site and underneath vein. Also, the toxicological analysis of the empty syringe found at the crime scene revealed the presence of atracurium, confirming that the victim had administered a lethal dose of atracurium.

摘要

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