J Drugs Dermatol. 2024 Oct 1;23(10):847-851. doi: 10.36849/JDD.2024.8056.
Atopic dermatitis (AD) is one of the most prevalent inflammatory skin conditions, characterized by recurrent eczema with varying degrees of erythema, pruritus, xerosis, and pain. Although there are many treatment options for AD, efficacy is limited by poor adherence, especially for topical medications. Patient preferences for certain vehicle formulations and frequencies of administration, as well as patient aversion to certain adverse effects, can negatively impact adherence and treatment success. Discrete choice experiments (DCEs) are used to assess preferences in a manner comparable to clinical decision-making. Six discrete choice experiments on AD were analyzed to create a comprehensive data sheet of patient and physician preferences for medication. When choosing a medication, skin clearance, itch relief, and flexible treatments were most important to patients. J Drugs Dermatol. 2024;23(10):847-851. doi:10.36849/JDD.8056.
特应性皮炎（AD）是最常见的炎症性皮肤疾病之一，其特征为反复发作的湿疹，伴有不同程度的红斑、瘙痒、干燥和疼痛。尽管 AD 有许多治疗选择，但疗效受到较差的依从性限制，尤其是对于局部药物治疗。患者对某些载体配方和给药频率的偏好，以及对某些不良反应的厌恶，会对依从性和治疗效果产生负面影响。离散选择实验（DCE）用于以类似于临床决策的方式评估偏好。对 6 项 AD 离散选择实验进行了分析，以创建一份关于患者和医生对药物偏好的综合数据表。在选择药物时，患者最看重皮肤清除率、瘙痒缓解和灵活的治疗方案。J 皮肤病药物杂志。2024;23(10):847-851。doi:10.36849/JDD.8056。
