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严重狼疮性肠炎:一个诊断和治疗的谜团。

Severe lupus enteritis: A diagnostic and therapeutic enigma.

机构信息

Paediatric Immunology and Rheumatology Unit, Aster CMI Hospital, Bengaluru, India.

Department of Radiology, Aster CMI Hospital, Bengaluru, India.

出版信息

Lupus. 2024 Nov;33(13):1483-1486. doi: 10.1177/09612033241290579. Epub 2024 Oct 3.

DOI:10.1177/09612033241290579
PMID:39361807
Abstract

Lupus enteritis refers to the gastrointestinal involvement in systemic lupus erythematosus (SLE). It presents with diverse symptoms that frequently overlap with those of other acute abdominal conditions, posing diagnostic challenges. We describe an adolescent female, with lupus pancreatitis and nephritis, who later developed severe lupus enteritis during the course of her illness. She was treated with pulse methylprednisolone and intravenous cyclophosphamide and gradually improved over 3 weeks. Our case highlights the need to consider lupus enteritis in patients with severe pain abdomen and intractable vomiting. Presence of lupus pancreatitis and nephritis are risk factors for development of enteritis.

摘要

狼疮性肠炎是指系统性红斑狼疮(SLE)累及胃肠道。其表现多样,常与其他急腹症相重叠,给诊断带来挑战。我们描述了一例患有狼疮性胰腺炎和肾炎的青少年女性,在病程中后来出现严重的狼疮性肠炎。她接受了脉冲甲基强的松龙和静脉环磷酰胺治疗,病情在 3 周内逐渐好转。我们的病例强调了在出现严重腹痛和顽固性呕吐的患者中要考虑狼疮性肠炎的可能性。狼疮性胰腺炎和肾炎的存在是肠炎发展的危险因素。

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