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采用双补片和右心室心尖外排除技术修复“奶酪蛋糕样”室间隔缺损:中期随访结果。

Surgical repair of "Swiss Cheese" ventricular septal defects with two-patch and right ventricular apex-exclusion technique: mid-term follow-up results.

机构信息

Heart Center, Affiliated Women and Children's Hospital, Qingdao University, Qingdao, 266000, China.

出版信息

J Cardiothorac Surg. 2024 Oct 3;19(1):584. doi: 10.1186/s13019-024-03085-z.

Abstract

BACKGROUND

"Swiss Cheese" ventricular septal defects represent a serious congenital heart disease with suboptimal clinical outcomes and a lack of consensus regarding its management. This study presents mid-term follow-up results of surgical repairs for "Swiss Cheese" ventricular septal defects, utilizing the two-patch and right ventricle apex-exclusion technique.

METHODS

A retrospective review was conducted on 13 patients who underwent surgical repair utilizing the two-patch and right ventricle apex-exclusion technique at our institution between May 2014 and October 2021. The procedure involved the closure of defects in the outflow tract ventricular septal and the apex trabecular ventricular septal regions using two patches, with concurrent exclusion of the right ventricular apex from the right ventricular inflow tract.

RESULTS

Median follow-up was 4.9 ± 2.1 years (range: 2-9 years). All cases were successful without mortality or major complications. Two years post-surgery, cardiac magnetic resonance revealed median values for left ventricular ejection fraction, right ventricular ejection fraction, left ventricular end-diastolic volume and right ventricular end-diastolic volume of 63.9% ± 1.8% (range: 61-67%), 49.2% ± 2.6% (range: 46-55%), 39.15 ± 2.11 ml (range: 36.2-42.7 ml), 44.55 ± 3.33 ml (range: 38.7-48.6 ml), respectively. No thrombosis occurred. The latest echocardiography results confirmed normal cardiac function in all cases.

CONCLUSIONS

The surgical repair of "Swiss Cheese" ventricular septal defects utilizing the two-patch and right ventricle apex-exclusion technique is a viable approach with favorable mid-term outcomes. More cases and long-term follow-up results are needed to validate the feasibility and safety of this technique.

摘要

背景

“瑞士奶酪”型室间隔缺损是一种严重的先天性心脏病,临床结局不佳,其治疗方法也尚未达成共识。本研究报告了应用双补片加右室心尖外排除术治疗“瑞士奶酪”型室间隔缺损的中期随访结果。

方法

回顾性分析 2014 年 5 月至 2021 年 10 月在我院应用双补片加右室心尖外排除术治疗的 13 例患者。手术采用双补片修补流出道室间隔和小梁部室间隔缺损,同时将右室心尖从右室流入道排除在外。

结果

中位随访时间为 4.9±2.1 年(范围:2-9 年)。所有患者均手术成功,无死亡或重大并发症。术后 2 年,心脏磁共振检查显示左心室射血分数、右心室射血分数、左心室舒张末期容积和右心室舒张末期容积的中位数分别为 63.9%±1.8%(范围:61-67%)、49.2%±2.6%(范围:46-55%)、39.15±2.11ml(范围:36.2-42.7ml)和 44.55±3.33ml(范围:38.7-48.6ml)。无血栓形成。最新的超声心动图结果证实所有患者的心脏功能均正常。

结论

应用双补片加右室心尖外排除术治疗“瑞士奶酪”型室间隔缺损是一种可行的方法,具有良好的中期结果。需要更多的病例和长期随访结果来验证该技术的可行性和安全性。

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