Suppr超能文献

哌甲酯的处方管理:预防滥用还是妨碍多动症治疗依从性?

Scheduling of methylphenidate: Preventing misuse or impeding ADHD treatment adherence?

作者信息

Schoeman Renata, Weinberg Sophia

机构信息

Stellenbosch Business School, Bellville, South Africa.

出版信息

S Afr J Psychiatr. 2024 Sep 24;30:2335. doi: 10.4102/sajpsychiatry.v30i0.2335. eCollection 2024.

Abstract

BACKGROUND

Attention-deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, with a chronic, and potentially debilitating course if untreated. Medication adherence is poor - negatively affecting emotional, social, educational and employment outcomes. The current Schedule 6 status of methylphenidate (MPH) drives healthcare resource utilisation and costs - a potential barrier to care.

AIM

This study explored stakeholders' understanding and perceptions of the potential impact of a regulatory shift in the scheduling of MPH on treatment accessibility and adherence for ADHD.

SETTING

Participants from multiple stakeholder groups, involved in ADHD management in South Africa, were recruited via professional networks.

METHODS

A qualitative analysis of semi-structured interviews with 23 stakeholders was conducted to explore their views on the utility, benefits and risks associated with rescheduling MPH.

RESULTS

Six key themes emerged from the interviews: 'adherence', 'accessibility', 'affordability', 'stigma', 'rescheduling of MPH' and 'risk mitigation'. Core to these themes is the role of the scheduling of MPH - which can have a protective societal role, but also acts as a barrier to care for individuals with ADHD.

CONCLUSION

The current Schedule 6 status of MPH is not an effective strategy to prevent misuse and diversion but negatively impacts on treatment adherence. The positive outlook from stakeholders on rescheduling MPH holds significant implications for the ADHD landscape in South Africa.

CONTRIBUTION

It is crucial to address stigma, facilitate fundamental change in service delivery and remove structural and practical barriers to care to improve outcomes for individuals with ADHD. A framework for ADHD treatment adherence is provided.

摘要

背景

注意力缺陷多动障碍(ADHD)是一种常见的神经发育障碍,如果不进行治疗,其病程呈慢性且可能使人衰弱。药物依从性较差,会对情绪、社交、教育和就业结果产生负面影响。目前哌甲酯(MPH)的附表6状态推动了医疗资源的利用和成本,这可能成为治疗的障碍。

目的

本研究探讨了利益相关者对MPH监管分类变更对ADHD治疗可及性和依从性潜在影响的理解和看法。

背景

通过专业网络招募了来自南非参与ADHD管理的多个利益相关者群体的参与者。

方法

对23名利益相关者进行半结构化访谈,并进行定性分析,以探讨他们对MPH重新分类的效用、益处和风险的看法。

结果

访谈中出现了六个关键主题:“依从性”“可及性”“可负担性”“污名化”“MPH重新分类”和“风险缓解”。这些主题的核心是MPH的分类作用,它可以起到保护社会的作用,但也成为ADHD患者治疗的障碍。

结论

目前MPH的附表6状态并非防止滥用和转移的有效策略,反而对治疗依从性产生负面影响。利益相关者对MPH重新分类的积极看法对南非的ADHD格局具有重要意义。

贡献

解决污名化问题、促进服务提供的根本变革以及消除治疗的结构和实际障碍对于改善ADHD患者的治疗结果至关重要。提供了一个ADHD治疗依从性框架。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ede/11447588/c2affe161903/SAJPsy-30-2335-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验