Niu Zhongfeng, Chen Lujiao, Zhang Yanhua, Zhao Li
Department of Radiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Radiology, Shaoxing People's Hospital, Zhejiang, China.
Front Med (Lausanne). 2024 Sep 19;11:1453043. doi: 10.3389/fmed.2024.1453043. eCollection 2024.
A 20-year-old male patient with a 15-month history of recurrent cough and hemoptysis presented at our hospital with suspected pulmonary sparganosis. Computed Tomography (CT) revealed migratory and variable lesions ranging from patchy shadows to nodular and cavernous foci. Additionally, the location and morphology of the cavities changed rapidly. The patient's peripheral blood eosinophil count remained within the normal range throughout the course of the infection, and antibiotics (moxifloxacin) alleviated the symptoms. At the early stage of admission, there was a slight increase in neutrophil and basophil counts. Initial treatment with a standard dose of praziquantel led to a significant improvement in symptoms, but the symptoms soon relapsed. However, doubling the dose 4 months later eventually cured the disease. The migratory nature of the CT lesion and the presence of tunnel signs were key to diagnosing a parasitic infection. The variability and rapid changes in the lesion further facilitated the differentiation of the disease, which rarely manifests as a granulomatous cavity.
一名20岁男性患者，有15个月反复咳嗽和咯血病史，因疑似肺裂头蚴病到我院就诊。计算机断层扫描（CT）显示有游走性和多变性病变，范围从斑片状阴影到结节状和空洞状病灶。此外，空洞的位置和形态变化迅速。在整个感染过程中，患者外周血嗜酸性粒细胞计数保持在正常范围内，抗生素（莫西沙星）可缓解症状。入院初期，中性粒细胞和嗜碱性粒细胞计数略有增加。初始使用标准剂量吡喹酮治疗后症状有显著改善，但症状很快复发。然而，4个月后将剂量加倍最终治愈了该疾病。CT病变的游走性和隧道征的存在是诊断寄生虫感染的关键。病变的多变性和快速变化进一步有助于该病的鉴别，该病很少表现为肉芽肿性空洞。
