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[运动及儿茶酚胺诱发的室上性心动过速]

[Supraventricular tachycardia induced by effort and by catecholamines].

作者信息

Lévy S, Pierron J P, Eisinger J F, Franchi J, Faugère G, Valeix B, Marion J, Gérard R

出版信息

Arch Mal Coeur Vaiss. 1985 Sep;78(9):1431-6.

PMID:3936447
Abstract

The role played by catecholamines in the initiation of certain forms of ventricular tachycardia is now recognised. On the other hand, a similar predominant or exclusive mechanism has not been demonstrated in supraventricular tachycardia. We observed a rate case of reproducible attacks of junctional tachycardia on effort in a 45 year old man. This patient had experienced attacks of tachycardia on effort for a number of years, stopping about 10 minutes after the end of effort. An exercise stress test performed for an anginal attack, induced a narrow complex tachycardia at 270/min at the first minute of the recovery period which terminated spontaneously 18 minutes later after a brief episode of atrial fibrillation. During a second exercise stress test, an episode of tachycardia at 250/min was recorded at the second minute of recovery, lasting 11 minutes. Investigations showed a retrograde concealed septal bundle of Kent activated retrogradely during reciprocating tachycardia. A similar form of tachycardia was induced by an injection of isoproterenol. The adrenergic mechanism of the arrhythmia led to the prescription of a beta-blocker (propranolol 120 mg/day), which effectively prevented clinical tachycardia and the forms of tachycardia induced by ergometric tests 15 days and 3 months after the initiation of treatment.

摘要

儿茶酚胺在某些形式的室性心动过速起始中所起的作用现已得到认可。另一方面,在室上性心动过速中尚未证实存在类似的主要或唯一机制。我们观察到一例45岁男性在用力时反复出现交界性心动过速发作的病例。该患者多年来在用力时出现心动过速发作,在用力结束后约10分钟停止。为诊断心绞痛发作而进行的运动负荷试验在恢复期第1分钟诱发了频率为270次/分钟的窄QRS波心动过速,在短暂房颤发作后18分钟自行终止。在第二次运动负荷试验中,在恢复期第2分钟记录到一次频率为250次/分钟的心动过速发作,持续11分钟。检查显示存在一条逆行隐匿性肯特束,在折返性心动过速时逆向激活。静脉注射异丙肾上腺素诱发了类似形式的心动过速。心律失常的肾上腺素能机制促使处方使用β受体阻滞剂(普萘洛尔120毫克/天),在治疗开始后15天和3个月时,该药有效预防了临床心动过速以及运动负荷试验诱发的心动过速形式。

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