Mallory Allen B, Martin Jared K, Fitzpatrick Margaret M, Yilmazer Tansel, Chavez Laura, Slesnick Natasha
Department of Human Sciences, The Ohio State University, Columbus, Ohio, USA.
Department of Medicine, Center for Vulnerable Populations, University of California, San Francisco, San Francisco, California, USA.
LGBT Health. 2025 Apr;12(3):183-192. doi: 10.1089/lgbt.2023.0230. Epub 2024 Oct 4.
The purpose of this study was to examine differences in mental health outcomes of two groups within youth experiencing homelessness (YEH) and who have a substance use disorder (SUD): sexual minority (SM) and heterosexual females. This study used baseline data from four randomized clinical trials of substance use interventions for YEH with a SUD to examine differences in depression and suicidality between SM and heterosexual female youth. Participants were between 12 and 24 years of age. Meta-analytic methods were used to aggregate data across studies to estimate differences in mental health. Results indicated that female SM-YEH had higher depression symptoms (Hedge's []0.20; 95% confidence interval [CI] 0.01-0.39), higher risk of a history of suicide behavior (risk ratio 1.63; 95% CI: 1.17-2.27), and a greater number of suicide behaviors ( 0.31; 95% CI: 0.09-0.54) compared to their heterosexual peers. These effect sizes were not moderated by age. Female SM-YEH had elevated levels of depression and suicidality compared to their heterosexual peers. The findings of this study align with research on mental health disparities between SM and heterosexual youth generally, which underscores the unique struggles and risks associated with identifying as a female SM-YEH with a SUD.
本研究的目的是调查在经历无家可归且患有物质使用障碍（SUD）的青年群体中的两组人群——性少数群体（SM）和异性恋女性——在心理健康结果方面的差异。本研究使用了四项针对患有SUD的无家可归青年的物质使用干预随机临床试验的基线数据，以检验SM青年和异性恋女性青年在抑郁和自杀倾向方面的差异。参与者年龄在12至24岁之间。采用荟萃分析方法汇总各项研究的数据，以估计心理健康方面的差异。结果表明，与异性恋同龄人相比，性少数群体的无家可归青年女性有更高的抑郁症状（赫奇斯效应量[]0.20；95%置信区间[CI] 0.01 - 0.39）、更高的自杀行为史风险（风险比1.63；95% CI：1.17 - 2.27）以及更多的自杀行为（效应量0.31；95% CI：0.09 - 0.54）。这些效应量不受年龄的调节。与异性恋同龄人相比，性少数群体的无家可归青年女性的抑郁和自杀倾向水平更高。本研究的结果与关于性少数群体和异性恋青年之间心理健康差异的研究总体一致，该研究强调了作为患有SUD的性少数群体无家可归青年女性所面临的独特困境和风险。
