镰状颅骨内骨化的骨髓中 TSPO、COX-1 和 COX-2 摄取增加。
Increased TSPO, COX-1, and COX-2 Uptake in Bone Marrow Within a Falx Cerebri Ossification.
机构信息
From the Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD.
出版信息
Clin Nucl Med. 2024 Nov 1;49(11):e604-e605. doi: 10.1097/RLU.0000000000005491. Epub 2024 Oct 3.
Ossification is uncommon, generally asymptomatic, and often incidentally identified in imaging studies. We report on a 54-year-old man who participated as a healthy volunteer in a clinical trial using PET imaging to investigate neuroinflammation. An incidental ossified lesion in the anterior falx cerebri was revealed by MRI. CT scan showed a small hypodense center in the lesion, probably corresponding to bone marrow. The PET scans using 18 F-SF51, 11 C-PS13, and 11 C-MC1 showed increased uptake within this lesion, which was probably related to bone marrow activity within the ossification.
骨化不常见，通常无症状，常在影像学研究中偶然发现。我们报告了一例 54 岁男性，他作为健康志愿者参加了一项使用 PET 成像研究神经炎症的临床试验。MRI 显示大脑镰前部有一处意外的骨化病变。CT 扫描显示病变中有一个小的低密中心，可能对应骨髓。使用 18 F-SF51、11 C-PS13 和 11 C-MC1 的 PET 扫描显示该病变内摄取增加，这可能与骨化内骨髓活性有关。
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