[大鼠脑自发转化星形胶质细胞新细胞系的分离与鉴定]
[Isolation and characterization of a new cell line of spontaneously transformed astrocytes of the rat brain].
作者信息
Mersel M, Tholey G, Delaunoy J P, Rebel G, Flory E, Mandel P
出版信息
C R Acad Sci III. 1985;301(19):811-5.
PMID:3936606
Abstract
A new cell line of transformed astrocytes was obtained from primary new born rat brain cultures. rat brain cultures. These transformed cell line possess a normal karyotype, a doubling time of 17-24 hrs. and astrocyte specific protein marquers: glial fibrillar acidic protein (GFA) and glutamine synthetase. The ganglioside pattern is more differentiated than that of other known astrocyte lines.
摘要
一种新的转化星形胶质细胞系是从新生大鼠脑原代培养物中获得的。这些转化细胞系具有正常的核型，倍增时间为17 - 24小时，以及星形胶质细胞特异性蛋白标志物：胶质纤维酸性蛋白（GFA）和谷氨酰胺合成酶。其神经节苷脂模式比其他已知星形胶质细胞系的更具分化性。
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