Kirk Frazer, Yong Matthew S, Tran Lavinia, Newcomb Andrew, He Cheng, Stroebel Andrie
Department of Cardiothoracic Surgery, Gold Coast University Hospital, Gold Coast, Qld, Australia; School of Medicine and Dentistry, Griffith University, Gold Coast, Qld, Australia; College of Medicine and Dentistry, James Cook University, Townsville, Qld, Australia.
Department of Cardiothoracic Surgery, Gold Coast University Hospital, Gold Coast, Qld, Australia; School of Medicine and Dentistry, Griffith University, Gold Coast, Qld, Australia.
Heart Lung Circ. 2024 Dec;33(12):1627-1637. doi: 10.1016/j.hlc.2024.07.007. Epub 2024 Oct 4.
This study aimed to examine contemporary burden and treatment trends of atrial fibrillation (AF) in patients undergoing cardiac surgery in Australia and New Zealand. This allows comparison of contemporary practice with the Society of Thoracic Surgeons guideline recommendations for the surgical treatment of AF in patients undergoing cardiac surgery.
A 10-year retrospective review of the Australian & New Zealand Society of Cardiac & Thoracic Surgeons National Cardiac Surgery Database was performed, examining all adult cardiac surgery patients from 2011 to 2021. Patients were grouped by the presence or absence of AF, and simple descriptive statistical analysis was performed to assess baseline demographics and premorbid condition of the patients. The incidence of AF was analysed by type of surgery. Trends for surgical treatment of AF were then analysed using simple descriptive statistics, examining isolated left atrial appendage ligation, isolated surgical ablation, and combined ligation and ablation.
In the last 10 years, the Australian & New Zealand Society of Cardiac & Thoracic Surgeons database has recorded 140,680 patients who underwent cardiac surgery. Atrial fibrillation (AF) was present in 21,077 patients (14%). Patients with AF were generally older (72.25 vs 66.65 years; p<0.001). Among patients undergoing cardiac surgery, AF was more common in female than in male patients (18% vs 13%, respectively). Patients with AF more often had a higher classification of dyspnoea according to the New York Heart Association and lower ejection fractions compared with their AF-free counterparts. The incidence of AF as a comorbid condition was more frequent in patients undergoing mitral valve surgery or combined coronary artery bypass grafting and valve surgery (aortic, mitral, or both) compared with those undergoing isolated coronary or aortic surgery. Only 11.90% (n=2,509) of patients with AF received a combined ablation and left atrial appendage ligation, and 19.54% (n=693) of those received a Cox-Maze IV ablation.
The burden of concomitant AF in patients undergoing cardiac surgery in Australia is higher than previously reported (14% vs 5%-11%). Despite strong recommendation for the surgical management of AF in patients undergoing cardiac surgery and clear evidence of its benefit, both left atrial appendage ligation and surgical ablation independently or concomitantly remain heavily underutilised in this cohort.
本研究旨在调查澳大利亚和新西兰接受心脏手术患者的心房颤动(AF)的当代负担和治疗趋势。这使得能够将当代实践与胸外科医师协会关于心脏手术患者AF外科治疗的指南建议进行比较。
对澳大利亚和新西兰心脏与胸外科医师协会国家心脏手术数据库进行了为期10年的回顾性研究,检查了2011年至2021年期间所有成年心脏手术患者。根据是否存在AF对患者进行分组,并进行简单的描述性统计分析,以评估患者的基线人口统计学和病前状况。按手术类型分析AF的发生率。然后使用简单的描述性统计分析AF的外科治疗趋势,检查孤立性左心耳结扎、孤立性手术消融以及联合结扎和消融。
在过去10年中,澳大利亚和新西兰心脏与胸外科医师协会数据库记录了140,680例接受心脏手术的患者。21,077例患者(14%)存在心房颤动(AF)。AF患者通常年龄较大(72.25岁对66.65岁;p<0.001)。在接受心脏手术的患者中,AF在女性中比在男性中更常见(分别为18%和13%)。与无AF的患者相比,AF患者根据纽约心脏协会的呼吸困难分级更高,射血分数更低。与接受孤立性冠状动脉或主动脉手术的患者相比,AF作为合并症在接受二尖瓣手术或冠状动脉搭桥术与瓣膜手术(主动脉、二尖瓣或两者)联合手术的患者中更常见。只有11.90%(n = 2,509)的AF患者接受了联合消融和左心耳结扎,其中19.54%(n = 693)接受了Cox-Maze IV消融。
澳大利亚接受心脏手术患者中合并AF的负担高于先前报道(14%对5%-11%)。尽管强烈建议对心脏手术患者进行AF的外科治疗且有明确的益处证据,但在该队列中,左心耳结扎和手术消融单独或联合使用的情况仍然严重未得到充分利用。