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低能量体外冲击波治疗深真皮和皮下纤维化各种病变的临床疗效和安全性。

Clinical Efficacy and Safety of Low-Energy Extracorporeal Shock Wave Therapy for Various Conditions of Deep Dermal and Subdermal Fibrosis.

机构信息

Ko Jung A Clinic, Seoul, South Korea.

Yonsei Seran Dermatology and Laser Clinic, Seoul, South Korea.

出版信息

Skin Res Technol. 2024 Oct;30(10):e70082. doi: 10.1111/srt.70082.

DOI:10.1111/srt.70082
PMID:39366905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11452247/
Abstract

BACKGROUND

Extracorporeal shock wave therapy (ESWT) enhances extracellular matrix remodeling and tissue regeneration by promoting growth factor release, regulating blood and lymphatic flows, and reducing fat and fibrotic tissues. Focused shock wave therapy (F-SWT), radial shock wave therapy (R-SWT), and combined F-SWT and R-SWT have been used to deliver different patterns of shock energy depending on the characteristics of the target lesions.

METHODS

We investigated the efficacy and safety of ESWT in patients with dermal and subdermal fibrosis. Fifty-two patients treated with F-SWT and/or R-SWT for dermal and subdermal fibrosis caused due to various reasons were retrospectively analyzed by reviewing their medical records, clinical images, and ultrasound study images.

RESULTS

The mean number of pulses administered for F-SWT on the cheek, temple, and chin were 2600.0 ± 1040.8 shocks/session and for R-SWT were 5080.0 ± 2234.6 pulses/session, and the number of treatment sessions were 8.0 ± 4.4. In patients who were treated with ESWT on the abdomen, the mean number of pulses for F-SWT were 2600.0 ± 2408.3 shocks/session and for R-SWT were 8400.0 ± 894.4 pulses/session, and the number of treatment sessions were 3.2 ± 1.6. Most patients were satisfied with the results. Pain during ESWT was well tolerated and post-ESWT edema was more common in R-SWT than in F-SWT.

CONCLUSION

Our data demonstrated that ESWT effectively and safely improved the clinical appearance and functional movement of patients with dermal and subdermal fibrosis caused due to various reasons.

摘要

背景

体外冲击波疗法(ESWT)通过促进生长因子释放、调节血液和淋巴流动以及减少脂肪和纤维组织来增强细胞外基质重塑和组织再生。聚焦式冲击波疗法(F-SWT)、径向冲击波疗法(R-SWT)以及 F-SWT 和 R-SWT 的联合应用,根据靶病变的特点,提供了不同模式的冲击波能量。

方法

我们研究了 ESWT 治疗各种原因引起的真皮和皮下纤维化的疗效和安全性。通过回顾病历、临床图像和超声研究图像,对 52 例因各种原因导致真皮和皮下纤维化而接受 F-SWT 和/或 R-SWT 治疗的患者进行了回顾性分析。

结果

F-SWT 在面颊、太阳穴和下巴的平均脉冲数为 2600.0±1040.8 次/次,R-SWT 为 5080.0±2234.6 次/次,治疗次数为 8.0±4.4 次。接受 ESWT 治疗腹部的患者中,F-SWT 的平均脉冲数为 2600.0±2408.3 次/次,R-SWT 为 8400.0±894.4 次/次,治疗次数为 3.2±1.6 次。大多数患者对结果满意。ESWT 期间的疼痛可耐受,R-SWT 比 F-SWT 更常见治疗后水肿。

结论

我们的数据表明,ESWT 有效且安全地改善了各种原因引起的真皮和皮下纤维化患者的临床外观和功能运动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/ab4927d7ff68/SRT-30-e70082-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/fbddf6f29285/SRT-30-e70082-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/04c4c091c3a7/SRT-30-e70082-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/f75a9c3db804/SRT-30-e70082-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/54fd6e1b09cf/SRT-30-e70082-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/ab4927d7ff68/SRT-30-e70082-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/fbddf6f29285/SRT-30-e70082-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/04c4c091c3a7/SRT-30-e70082-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/f75a9c3db804/SRT-30-e70082-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/54fd6e1b09cf/SRT-30-e70082-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dab5/11452247/ab4927d7ff68/SRT-30-e70082-g005.jpg

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