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2023 年埃塞俄比亚产科瘘管病康复时间的系统评价和荟萃分析。

A systematic review and meta-analysis on the recovery time of obstetric fistula in Ethiopia, 2023.

机构信息

Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.

出版信息

BMC Womens Health. 2024 Oct 4;24(1):547. doi: 10.1186/s12905-024-03391-7.

Abstract

INTRODUCTION

Obstetric fistula is a birth injury that causes the vagina to open abnormally. As a result, women may experience urinary leakage, which can lead to isolation, depression, and a lower quality of life. Due to the scarcity of evidence regarding the average recovery time for obstetric fistula in Ethiopia, Therefore, this study aimed to assess the recovery time for women with obstetric fistula in Ethiopia.

METHODS

Between September and 8 November 2023, published studies were searched using online databases including PubMed, Hinari, Epistemonikos, and Google Scholar. The systematic review was conducted following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Study quality was assessed using Egger's test and a visual inspection of funnel plot symmetry. Statistical analysis was performed using STATA version 17 software. A random-effects model was employed for analysis, and the Cochrane Q-test and I² statistics were used to assess heterogeneity among studies.

RESULT

A total of six studies were included in this analysis. The minimum and maximum median survival times were 2.67 and 5.19 weeks, respectively. The pooled median recovery time was 4.05 weeks (95% CI: 2.92, 5.18) based on the random effects model. Heterogeneity among the included studies assessed by the I² statistic was 97.72% (p = 0.000). The p-value for Egger's regression test (0.017) was significant, indicating evidence of publication bias.

CONCLUSION

The findings reveal a pooled median recovery time of 4.05 weeks, with considerable heterogeneity. Although these figures provide valuable insights, the presence of publication bias was evidenced by the asymmetric funnel plot and significant Egger's test. Efforts to address publication bias are essential to improve future meta- the reliability of the surveys has increased.

REGISTRATION

The protocol for this systematic review was pre-registered on the International Prospective Register of Systematic Reviews (Registration Number: CRD42023270497).

摘要

介绍

产科瘘是一种分娩损伤,导致阴道异常张开。结果,女性可能会出现尿漏,这可能导致隔离、抑郁和生活质量下降。由于缺乏关于埃塞俄比亚产科瘘管平均恢复时间的证据,因此,本研究旨在评估埃塞俄比亚产科瘘管女性的恢复时间。

方法

2023 年 9 月至 11 月 8 日,使用在线数据库(包括 PubMed、Hinari、Epistemonikos 和 Google Scholar)搜索已发表的研究。系统评价遵循系统评价和荟萃分析的首选报告项目(PRISMA)标准进行。使用 Egger 检验和漏斗图对称性的视觉检查评估研究质量。使用 STATA 版本 17 软件进行统计分析。采用随机效应模型进行分析,使用 Cochrane Q 检验和 I² 统计量评估研究之间的异质性。

结果

共有六项研究纳入了本分析。最小和最大中位生存时间分别为 2.67 和 5.19 周。基于随机效应模型,汇总的中位恢复时间为 4.05 周(95%CI:2.92,5.18)。I² 统计量评估的纳入研究之间的异质性为 97.72%(p=0.000)。Egger 回归检验的 p 值(0.017)为显著,表明存在发表偏倚的证据。

结论

研究结果显示,中位恢复时间的汇总值为 4.05 周,异质性较大。尽管这些数据提供了有价值的见解,但不对称的漏斗图和显著的 Egger 检验表明存在发表偏倚。为了提高未来荟萃分析的可靠性,必须解决发表偏倚问题。

登记

本系统评价的方案已在国际前瞻性系统评价登记处(注册编号:CRD42023270497)预先注册。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8beb/11451168/f470da37c412/12905_2024_3391_Fig1_HTML.jpg

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