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因肉芽肿性颈淋巴结病接受外科手术的儿童中可识别病原体的发生率。

Incidence of an Identifiable Organism in Children Who Underwent a Surgical Procedure for Granulomatous Cervical Lymphadenopathy.

作者信息

Osterbauer Beth, Sahyouni Grace, LePhong Christopher, Dien Bard Jennifer, Vu My H, Koempel Jeffrey

机构信息

Division of Otolaryngology-Head and Neck Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA.

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

出版信息

Ear Nose Throat J. 2024 Oct 5:1455613241288469. doi: 10.1177/01455613241288469.

Abstract

The incidence of cervical lymphadenopathy due to nontuberculous mycobacteria is rising in the pediatric population. Our goal with this study was to review the number of pediatric patients with granulomatous cervical adenitis and determine the incidence of identification of a specific organism as both healthcare providers and parents are interested in identifying the causative pathogen. A retrospective chart review was conducted of patients at a high-volume tertiary care children's hospital between 2017 and 2023. Children were included if they underwent a surgical procedure for lymphadenopathy. Pathology, microbiology, and other laboratory reports were reviewed to document the presence of granulomatous cervical adenitis and the incidence of identification of a specific organism. Additional data collected included patient demographics and type of procedure. Of the 1538 charts reviewed, 163 patients underwent an inclusionary procedure. Mean patient age was 10.7 years (range 2.4 months-20 years), 70 (43%) were female, 25 (15%) had granulomatous cervical adenitis, and a specific organism was identified in 9 of these. Despite the availability of a number of ancillary tests, our data demonstrate that the identification of a specific pathogen in cases of granulomatous cervical lymphadenitis is rare. As a result, physicians should be prepared to rely primarily on the history and physical exam findings to determine a working diagnosis as well as a medical and/or surgical treatment plan.

摘要

非结核分枝杆菌所致小儿颈淋巴结病的发病率在儿科人群中呈上升趋势。我们开展这项研究的目的是回顾肉芽肿性颈淋巴结炎患儿的数量,并确定明确特定病原体的发生率,因为医疗服务提供者和家长都希望找出致病病原体。对一家大型三级儿童医院2017年至2023年期间的患者进行了回顾性病历审查。如果儿童因淋巴结病接受了外科手术,则纳入研究。对病理、微生物学及其他实验室报告进行审查,以记录肉芽肿性颈淋巴结炎的存在情况以及明确特定病原体的发生率。收集的其他数据包括患者人口统计学资料和手术类型。在审查的1538份病历中,163例患者接受了符合纳入标准的手术。患者平均年龄为10.7岁(范围2.4个月至20岁),70例(43%)为女性,25例(15%)患有肉芽肿性颈淋巴结炎,其中9例明确了特定病原体。尽管有许多辅助检查可用,但我们的数据表明,在肉芽肿性颈淋巴结炎病例中明确特定病原体的情况很少见。因此,医生应准备好主要依靠病史和体格检查结果来确定初步诊断以及药物和/或手术治疗方案。

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