Effects of over 10 weeks of resistance training on muscle and bone mineral density in older people with sarcopenia over 70 years old: A systematic review and meta-analysis of randomized controlled trials.

We aimed to examine the effects of more than 10 weeks of resistance training (RT) on muscle structure, muscle function, and bone mineral density (BMD) in older people with sarcopenia over 70 years old METHODS: PubMed, Web of Science, Embase, MEDLINE, Cochrane Library, and CINAHL databases were searched for randomized controlled trials. Standardized mean difference (MD) or standard mean difference (SMD) was used to pool the effect of the RT intervention RESULTS: Thirteen studies with 2080 older adults with sarcopenia were included. Resistance exercise significantly affected handgrip strength (MD = 1.67 kg; P = 0.02) and isometric muscle strength (standard mean difference [SMD] = 0.53; P = 0.02). Significant differences in chair stand test (SMD = 0.40; P = 0.02) and skeletal muscle mass index (mean difference [MD] = 1.67 kg/m; P = 0.0002) were found between the RT and control groups CONCLUSION: More than 10 weeks of RT has beneficial effects on muscle but no favorable effect on BMD in older people with sarcopenia over 70 years old.