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高级别非小细胞肺癌手术后的计算机断层扫描随访间隔与生存无关。

The Interval of Computed Tomography Follow-Ups after Advanced Non-Small-Cell Lung Cancer Surgery Did Not Show Any Relationship with Survival.

机构信息

Department of Thoracic Surgery, Kansai Medical University, Hirakata, Osaka, Japan.

出版信息

Ann Thorac Cardiovasc Surg. 2024;30(1). doi: 10.5761/atcs.oa.24-00093.

Abstract

PURPOSE

There is limited evidence concerning the computed tomography (CT) follow-up interval to detect recurrence and second primary cancers after surgery for non-small-cell lung cancer (NSCLC). In this study, we aimed to investigate the impact of CT interval on survival after surgery.

METHODS

This retrospective study analyzed the prognosis of 103 patients who underwent periodic CT after complete resection for pathological stage II-III NSCLC at a single institute between 2015 and 2020. The patients were stratified based on the follow-up CT intervals into the half-year group (Group H) and annual group (Group A). Additionally, the underlying differences in clinical backgrounds between the 2 groups were adjusted by propensity score matching.

RESULTS

A total of 103 patients (Group H, 76 patients; Group A, 27 patients) were included in this study. The 5-year overall survival (OS) rates in the unmatched cohort were 83.5% and 95.2% in groups H and A, respectively ( P = 0.17). Among the matched cohort, 42 and 21 patients were in groups H and A. The 5-year OS rates of the matched cohort were 89.8% and 94.4% in groups H and A ( P = 0.45), with no significant difference.

CONCLUSIONS

There was no association between CT intervals and postoperative survival.

摘要

目的

关于非小细胞肺癌(NSCLC)手术后用于检测复发和第二原发癌的计算机断层扫描(CT)随访间隔,目前相关证据有限。本研究旨在探讨 CT 间隔对手术后生存的影响。

方法

本回顾性研究分析了 2015 年至 2020 年在一家机构接受完全切除术后定期 CT 检查的病理分期 II-III 期 NSCLC 患者 103 例的预后。患者根据随访 CT 间隔分为半年组(H 组)和年度组(A 组)。此外,通过倾向评分匹配调整了两组之间临床背景的潜在差异。

结果

共有 103 例患者(H 组 76 例,A 组 27 例)纳入本研究。未匹配队列中,H 组和 A 组的 5 年总生存率(OS)分别为 83.5%和 95.2%(P=0.17)。在匹配队列中,H 组和 A 组分别有 42 例和 21 例患者。匹配队列的 5 年 OS 率分别为 H 组和 A 组的 89.8%和 94.4%(P=0.45),无显著差异。

结论

CT 间隔与术后生存无关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d190/11466525/779380c0bf0b/atcs-30-1-24-00093-figure01.jpg

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