Darby Juanita E, Akpotu Ivy C, Wi Dahee, Ahmed Sarah, Doorenbos Ardith Z, Lofton Saria
College of Nursing, University of Illinois Chicago, Chicago, IL.
College of Nursing, University of Illinois Chicago, Chicago, IL.
Pain Manag Nurs. 2025 Feb;26(1):e1-e9. doi: 10.1016/j.pmn.2024.09.002. Epub 2024 Oct 6.
Sickle cell disease (SCD) is a hereditary blood disorder with chronic pain that affects over 100,000 people in the United States. Previous research suggests a complex interaction between SCD pain outcomes and social determinants of health (SDOH).
To explore the impact of SDOH on pain outcomes in SCD.
We used a scoping review design to explore the broad topic of social factors that affect SCD pain.
We searched the PubMed/MEDLINE, CINAHL, and Embase databases using combined search and Medical Subject Headings terms ("social determinants of health," "sickle cell," and "pain").
We used a content analysis with a summative approach to identify and describe interactions between SDOH and SCD pain outcomes.
Eight articles reporting studies with 7,992 total participants and a focus on SCD pain outcomes met the inclusion criteria. Three themes related to SDOH and pain were produced: education and employment, social and emotional functioning, and healthcare access.
The key findings highlight the complex interplay between socioeconomic, psychological, and biological factors in SCD pain experiences. This underscores the need for nursing care to consider SDOH in an integrated, holistic approach to SCD pain.
To improve pain management among their SCD patients, nurses can assess pain holistically, develop customized individual pain management plans with educational and health literacy support options, and strengthen social support.
镰状细胞病（SCD）是一种遗传性血液疾病，伴有慢性疼痛，在美国影响着超过10万人。先前的研究表明，SCD疼痛结局与健康的社会决定因素（SDOH）之间存在复杂的相互作用。
探讨SDOH对SCD疼痛结局的影响。
我们采用了范围综述设计，以探讨影响SCD疼痛的社会因素这一广泛主题。
我们使用联合检索词和医学主题词（“健康的社会决定因素”、“镰状细胞”和“疼痛”）在PubMed/MEDLINE、CINAHL和Embase数据库中进行检索。
我们采用内容分析法和总结性方法来识别和描述SDOH与SCD疼痛结局之间的相互作用。
八篇报告研究的文章符合纳入标准，这些研究共有7992名参与者，重点关注SCD疼痛结局。产生了与SDOH和疼痛相关的三个主题：教育与就业、社会和情感功能以及医疗保健可及性。
主要研究结果突出了SCD疼痛经历中社会经济、心理和生物学因素之间的复杂相互作用。这强调了护理在以综合、整体的方法处理SCD疼痛时需要考虑SDOH。
为了改善SCD患者的疼痛管理，护士可以进行全面的疼痛评估，制定包含教育和健康素养支持选项的个性化疼痛管理计划，并加强社会支持。
