Yoshida K, Kawaguchi H, Hasegawa S, Muto T
Nihon Geka Gakkai Zasshi. 1985 Sep;86(9):1135-7.
Incidence of juxta papillary duodenal diverticula (JPDD) was studied in 182 patients with benign biliary diseases. Incidences of JPDD were 11.1% in cholecystolithiasis, 23.4% in cholecystocholedocholithiasis and 54.5% in choledocholithiasis. Concerning to the patients with common duct stones, average of age was significantly higher in the group with diverticulum than in the group without diverticulum (65.9 +/- 7.6 vs 55.9 +/- 13.7, p less than 0.01). Diameter of the common duct was also significantly larger in the group with diverticulum. To exclude the effect of aging, the same comparison was performed in patients older than 60 years. Here again, the group with diverticulum showed significantly greater dilatation of the common duct. Incidences of JPDD in the primary and secondary common duct stones were 73.1% and 19.7%, respectively. The difference was highly significant. JPDD seemed to play an important role in the pathogenesis of cholestasis in the aged patients which may result in formation of primary common duct stones.
对182例良性胆道疾病患者的十二指肠乳头旁憩室(JPDD)发病率进行了研究。胆囊结石患者中JPDD的发病率为11.1%,胆囊胆总管结石患者中为23.4%,胆总管结石患者中为54.5%。对于胆总管结石患者,有憩室组的平均年龄显著高于无憩室组(65.9±7.6岁对55.9±13.7岁,p<0.01)。有憩室组的胆总管直径也显著更大。为排除年龄因素的影响,对60岁以上患者进行了同样的比较。同样,有憩室组的胆总管扩张也更显著。原发性和继发性胆总管结石中JPDD的发病率分别为73.1%和19.7%。差异非常显著。JPDD似乎在老年患者胆汁淤积的发病机制中起重要作用,这可能导致原发性胆总管结石的形成。