Jinhua University of Vocational Technology, Jinhua 321000, China.
School of Chemistry and Molecular Engineering, Shanghai Key Laboratory for Urban Ecological Processes and Eco-Restoration, East China Normal University, 500 Dongchuan Road, Shanghai 200241, China.
Anal Methods. 2024 Nov 14;16(44):7527-7533. doi: 10.1039/d4ay01627k.
This research presents a highly sensitive and selective electrochemical sensor for detecting paracetamol. The sensor is created using laser direct-writing on a flexible PI substrate to form LIG electrodes. Gold nanoparticles (AuNPs) are then synthesized on the working electrode through secondary laser reduction, resulting in an AuNPs/LIG composite. This combination enhances the sensor's electrochemical activity, electron transfer rate, and adsorption capacity. The sensor exhibits a linear response to paracetamol concentrations with a detection limit of 0.086 μM. Testing on Tylenol tablets and tap water showed good recovery rates. The sensor displays strong anti-interference, reproducibility, and stability, making it a promising tool for effective paracetamol monitoring in real-world situations.
本研究提出了一种用于检测扑热息痛的高灵敏度和选择性电化学传感器。该传感器是通过在柔性 PI 基底上使用激光直写技术形成 LIG 电极制成的。然后通过二次激光还原在工作电极上合成金纳米粒子（AuNPs），形成 AuNPs/LIG 复合材料。这种组合提高了传感器的电化学活性、电子转移速率和吸附能力。该传感器对扑热息痛浓度表现出线性响应，检测限为 0.086 μM。对泰诺片剂和自来水的测试显示出良好的回收率。该传感器显示出较强的抗干扰性、重现性和稳定性，使其成为在实际情况下有效监测扑热息痛的有前途的工具。
